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Catalog Number:
33327
4-Methoxytrityl chloride resin (1.0 - 1.6 mmol/g, 200 - 400 mesh)
Documents
$29.34 /1G
Pack Size Availability Price
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Product Information

4-Methoxytrityl chloride resin is a highly versatile and efficient reagent widely utilized in organic synthesis and peptide chemistry. This resin, characterized by its functional group density of 1.0 - 1.6 mmol/g and a mesh size of 200 - 400, is particularly valuable for solid-phase synthesis applications. Its unique structure allows for the selective protection of hydroxyl groups, making it an essential tool in the synthesis of complex organic molecules and peptides. Researchers appreciate its ease of use and the ability to facilitate rapid purification processes, which significantly enhances overall workflow efficiency.

In addition to its role in organic synthesis, 4-Methoxytrityl chloride resin is also employed in the development of various pharmaceutical compounds, where precise control over functional groups is crucial. Its high stability and compatibility with a range of solvents make it suitable for diverse reaction conditions, allowing chemists to achieve high yields and purity. This resin stands out among similar compounds due to its superior reactivity and ease of removal, ensuring that it meets the rigorous demands of both academic and industrial applications.

MDL Number
MFCD00281965
Appearance
Yellow beads
Substitution
1.0 - 1.6 mmol/g
Mesh Size
200 - 400 mesh
Conditions
Store at 2-8 °C
%DVB
2% DVB
General Information
MDL Number
MFCD00281965
Appearance
Yellow beads
Substitution
1.0 - 1.6 mmol/g
Mesh Size
200 - 400 mesh
Conditions
Store at 2-8 °C
%DVB
2% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methoxytrityl chloride resin is widely utilized in research focused on:

  • DNA and RNA Synthesis: This resin is crucial in the solid-phase synthesis of oligonucleotides, allowing for efficient attachment of nucleotides during the assembly process.
  • Peptide Synthesis: It serves as a protective group in peptide synthesis, ensuring that specific amino acids are selectively modified without affecting others.
  • Drug Development: Researchers use this resin to create complex molecules, facilitating the development of new pharmaceuticals with targeted therapeutic effects.
  • Bioconjugation: The resin aids in attaching biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic and therapeutic agents.
  • Polymer Chemistry: It is employed in the synthesis of functional polymers, contributing to advancements in materials science and nanotechnology.

Citations