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Catalog Number:
33055
CAS Number:
50-89-5
Thymidine
Grade:
suitable for cell culture
Purity:
≥ 99% (HPLC)
Synonym(s):
2'-Deoxythymidine, 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
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Product Information

Thymidine is a nucleoside that plays a crucial role in the synthesis of DNA, making it essential for cellular replication and repair. This compound is widely utilized in molecular biology and biochemistry research, particularly in studies involving DNA synthesis, cell proliferation, and genetic engineering. Thymidine is also employed in the production of antiviral medications, as it can inhibit viral replication, making it a valuable asset in the pharmaceutical industry. Its unique structure allows for incorporation into DNA strands, which is pivotal for understanding genetic processes and developing therapeutic strategies.

In addition to its applications in research and pharmaceuticals, Thymidine is significant in the field of cancer treatment, where it is used to enhance the efficacy of certain chemotherapeutic agents. Its ability to support DNA synthesis makes it a vital component in various laboratory protocols, including those focused on cell culture and genetic manipulation. Researchers and industry professionals benefit from Thymidine's versatility and effectiveness, as it provides a reliable means to explore and manipulate genetic material.

Synonyms
2'-Deoxythymidine, 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
CAS Number
50-89-5
Purity
≥ 99% (HPLC)
Grade
suitable for cell culture
Molecular Formula
C10H14N2O5
Molecular Weight
242.23
MDL Number
MFCD00006537
PubChem ID
1134
Melting Point
185 - 190 ?C
Appearance
White to almost white crystalline powder
Optical Rotation
[a]D20 = +17.5 to +18.5 °(C=3 in water
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2'-Deoxythymidine, 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
CAS Number
50-89-5
Purity
≥ 99% (HPLC)
Grade
suitable for cell culture
Molecular Formula
C10H14N2O5
Molecular Weight
242.23
MDL Number
MFCD00006537
PubChem ID
1134
Melting Point
185 - 190 ?C
Appearance
White to almost white crystalline powder
Optical Rotation
[a]D20 = +17.5 to +18.5 °(C=3 in water
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Thymidine is widely utilized in research focused on:

  • DNA Synthesis: Thymidine is a crucial building block for DNA, making it essential in molecular biology for synthesizing DNA strands in vitro. This application is vital for genetic engineering and cloning projects.
  • Antiviral Research: It plays a significant role in the development of antiviral drugs, particularly those targeting viral replication. Researchers use thymidine to study the mechanisms of viruses like HIV and herpes simplex.
  • Cell Proliferation Studies: Thymidine incorporation assays are commonly used to measure cell proliferation. This is particularly important in cancer research, where understanding cell growth is critical for developing treatments.
  • Labeling in Imaging Techniques: Thymidine can be radioactively labeled, allowing scientists to track DNA synthesis and cell division in live organisms. This technique is beneficial in developmental biology and cancer research.
  • Gene Therapy: In gene therapy applications, thymidine is used to deliver therapeutic genes into target cells, enhancing the effectiveness of treatment for genetic disorders.

Citations