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Catalog Number:
33038
CAS Number:
143748-18-9
PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt
Synonym(s):
H-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 trifluoroacetate salt, Pituitary Adenylate Cyclae Activating Polypeptide-38 (6-38) (human, chicken, mouse, ovine, porcine, rat), FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
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Product Information

PACAP-38 (6-38) trifluoroacetate salt is a biologically active peptide known for its significant role in neuroprotection and neuroregulation. This compound is a member of the pituitary adenylate cyclase-activating polypeptide (PACAP) family, which has garnered attention in both research and therapeutic applications. Its unique structure allows it to interact with specific receptors in the nervous system, making it a valuable tool in studies related to neurodegenerative diseases, stress response, and metabolic regulation. Researchers have utilized PACAP-38 in various experimental models to explore its potential in enhancing cognitive function and protecting against neuronal damage.

In addition to its neuroprotective properties, PACAP-38 has been investigated for its role in modulating immune responses and promoting cell survival. Its applications extend to the fields of endocrinology and reproductive health, where it has been shown to influence hormone secretion and reproductive functions. The trifluoroacetate salt form enhances its solubility and stability, making it easier to handle in laboratory settings. With its diverse biological activities, PACAP-38 is an essential compound for researchers aiming to unlock new therapeutic avenues in neuroscience and beyond.

Synonyms
H-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 trifluoroacetate salt, Pituitary Adenylate Cyclae Activating Polypeptide-38 (6-38) (human, chicken, mouse, ovine, porcine, rat), FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
CAS Number
143748-18-9
Molecular Formula
C182H300N56O45S·C2HF3O2
Molecular Weight
4138.75
MDL Number
MFCD00165107
PubChem ID
131954572
Conditions
Store at ≤ -10 °C
General Information
Synonyms
H-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 trifluoroacetate salt, Pituitary Adenylate Cyclae Activating Polypeptide-38 (6-38) (human, chicken, mouse, ovine, porcine, rat), FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
CAS Number
143748-18-9
Molecular Formula
C182H300N56O45S·C2HF3O2
Molecular Weight
4138.75
MDL Number
MFCD00165107
PubChem ID
131954572
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

PACAP-38 (6-38) trifluoroacetate salt is widely utilized in research focused on

  • Neuroscience Research: This compound plays a crucial role in studying neuropeptide signaling pathways, providing insights into brain functions and potential treatments for neurological disorders.
  • Endocrinology: It is used to explore the regulation of hormonal responses, helping researchers understand the role of PACAP in stress responses and metabolic processes.
  • Cardiovascular Studies: The compound is investigated for its effects on cardiovascular health, particularly its potential to protect heart tissues and regulate blood flow.
  • Pharmacological Applications: PACAP-38 is being explored for its therapeutic potential in conditions like migraines and anxiety, offering a new avenue for drug development.
  • Cell Culture Experiments: Researchers utilize this compound to enhance cell survival and growth in vitro, which is essential for various biological studies and drug testing.

Citations