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Catalog Number:
33022
CAS Number:
1182723-43-8
Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt
Synonym(s):
Abz-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2trifluoroacetate salt, Abz-APP770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide
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$305.86 /1MG
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Product Information

Abz-Amyloid b/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt is a specialized peptide that plays a significant role in Alzheimer's disease research. This compound is particularly valuable for researchers studying amyloid-beta aggregation and its implications in neurodegenerative disorders. Its unique structure, featuring multiple arginine residues and a dinitrophenyl (Dnp) modification, enhances its binding affinity and stability, making it an ideal candidate for various biochemical assays and therapeutic applications.

In laboratory settings, this peptide can be utilized in the development of diagnostic tools and therapeutic strategies aimed at mitigating amyloid plaque formation. Its ability to mimic the amyloid precursor protein allows for detailed studies on the mechanisms of amyloid pathology, providing insights that could lead to innovative treatments. Additionally, the trifluoroacetate salt form ensures improved solubility and bioavailability, facilitating its use in both in vitro and in vivo experiments. This compound stands out for its potential to advance our understanding of Alzheimer's disease and contribute to the development of effective interventions.

Synonyms
Abz-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2trifluoroacetate salt, Abz-APP770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide
CAS Number
1182723-43-8
Molecular Formula
C69H114N26O18·C2HF3O2
Molecular Weight
1709.83
MDL Number
MFCD18782565
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Abz-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2trifluoroacetate salt, Abz-APP770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide
CAS Number
1182723-43-8
Molecular Formula
C69H114N26O18·C2HF3O2
Molecular Weight
1709.83
MDL Number
MFCD18782565
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Abz-Amyloid b/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate is widely utilized in research focused on:

  • Neuroscience Research: This compound is instrumental in studying Alzheimer’s disease, specifically in understanding the aggregation of amyloid-beta peptides, which are crucial in the pathology of the disease.
  • Drug Development: It serves as a valuable tool in the development of potential therapeutic agents aimed at preventing or reversing amyloid plaque formation, offering hope for effective treatments.
  • Diagnostic Tools: The compound can be used in the creation of assays that detect amyloid-beta levels in biological samples, aiding in early diagnosis of neurodegenerative diseases.
  • Biochemical Studies: Researchers utilize it to explore protein interactions and modifications, helping to elucidate mechanisms of action in cellular processes.
  • Peptide Synthesis: It plays a role in synthesizing modified peptides for various applications, including targeted drug delivery systems, enhancing the specificity and efficacy of treatments.

Citations