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Catalog Number:
33005
CAS Number:
113274-56-9
Hirudin (54-65) (desulfated) trifluoroacetate salt
Synonym(s):
H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OH trifluoroacetatesalt
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$136.00 /1MG
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Product Information

Hirudin (54-65) (desulfated) trifluoroacetate salt is a potent anticoagulant derived from the saliva of leeches, primarily used in medical and research applications. This compound is recognized for its ability to inhibit thrombin, making it invaluable in studies related to blood coagulation and cardiovascular health. Researchers utilize Hirudin in various experimental settings to explore its effects on blood clotting mechanisms, providing insights that can lead to the development of new anticoagulant therapies. Its unique structure allows for high specificity towards thrombin, offering advantages over other anticoagulants that may have broader effects.

In addition to its research applications, Hirudin is also being investigated for potential therapeutic uses in treating thrombotic disorders. Its desulfated form enhances stability and solubility, making it suitable for pharmaceutical formulations. The trifluoroacetate salt form further improves its bioavailability, which is crucial for effective treatment outcomes. As the demand for targeted anticoagulant therapies grows, Hirudin stands out as a promising candidate for both research and clinical applications, providing a pathway for advancements in thrombotic disease management.

Synonyms
H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OH trifluoroacetatesalt
CAS Number
113274-56-9
Molecular Formula
C66H93N13O25·C2HF3O2
Molecular Weight
1582.56
MDL Number
MFCD18782481
PubChem ID
16132569
Conditions
Store at ≤ -10 °C
General Information
Synonyms
H-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln-OH trifluoroacetatesalt
CAS Number
113274-56-9
Molecular Formula
C66H93N13O25·C2HF3O2
Molecular Weight
1582.56
MDL Number
MFCD18782481
PubChem ID
16132569
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Hirudin (54-65) (desulfated) trifluoroacetate salt is widely utilized in research focused on:

  • Anticoagulant Therapy: This compound is primarily used in the development of anticoagulant medications, providing a natural alternative to synthetic blood thinners. Its ability to inhibit thrombin makes it valuable in managing blood clotting disorders.
  • Biomedical Research: Researchers employ hirudin in studies related to cardiovascular health, particularly in exploring mechanisms of thrombosis and hemostasis. Its unique properties allow for detailed investigations into blood coagulation processes.
  • Diagnostic Applications: Hirudin is used in various diagnostic assays to measure thrombin activity, aiding in the assessment of clotting disorders and the effectiveness of anticoagulant therapies.
  • Drug Development: Pharmaceutical companies utilize hirudin as a lead compound in the design of new anticoagulant drugs, leveraging its natural origin and specific action on thrombin to create more effective therapies.
  • Research on Venom Components: The study of hirudin contributes to the understanding of how certain snake and leech venoms affect blood coagulation, which can lead to novel therapeutic strategies and drug discoveries.

Citations