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Catalog Number:
32998
CAS Number:
252256-43-2
(Val671-Amyloid β/A4 Protein Precursor770 (667-676) trifluoroacetate salt
Synonym(s):
H-Ser-Glu-Val-Lys-Val-Asp-Ala-Glu-Phe-Arg-OH trifluoroacetate salt, (Val671)-APP770 (667-676)
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Product Information

The (Val671)-Amyloid β/A4 Protein Precursor770 (667-676) trifluoroacetate salt is a specialized peptide that plays a crucial role in Alzheimer's disease research. This compound is integral for studying amyloid-beta peptide aggregation, which is a hallmark of Alzheimer's pathology. Researchers utilize this peptide to investigate the mechanisms of amyloid plaque formation and its implications in neurodegenerative diseases. Its trifluoroacetate salt form enhances solubility and stability, making it suitable for various biochemical assays and in vitro studies.

In addition to its applications in basic research, this compound can be pivotal in the development of therapeutic strategies aimed at modulating amyloid-beta levels. By providing insights into the structure-activity relationships of amyloid peptides, it aids in the design of potential inhibitors or modulators that could mitigate the effects of amyloid aggregation. This compound is particularly valuable for pharmaceutical companies and academic institutions focused on neurodegenerative disease research, offering a pathway to innovative treatments and deeper understanding of Alzheimer's disease mechanisms.

Synonyms
H-Ser-Glu-Val-Lys-Val-Asp-Ala-Glu-Phe-Arg-OH trifluoroacetate salt, (Val671)-APP770 (667-676)
CAS Number
252256-43-2
Molecular Formula
C51H82N14O18·C2HF3O2
Molecular Weight
1293.32
MDL Number
MFCD18782265
PubChem ID
91976973
Conditions
Store at ≤ -10 °C
General Information
Synonyms
H-Ser-Glu-Val-Lys-Val-Asp-Ala-Glu-Phe-Arg-OH trifluoroacetate salt, (Val671)-APP770 (667-676)
CAS Number
252256-43-2
Molecular Formula
C51H82N14O18·C2HF3O2
Molecular Weight
1293.32
MDL Number
MFCD18782265
PubChem ID
91976973
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(Val671)-Amyloid b/A4 Protein Precursor770 (667-676) trifluoroacetate salt is widely utilized in research focused on

  • Neuroscience Research: This compound plays a crucial role in studying Alzheimer's disease by mimicking amyloid-beta peptides, allowing researchers to investigate their aggregation and toxicity mechanisms.
  • Drug Development: It serves as a valuable tool in the development of therapeutic agents aimed at preventing or reversing amyloid plaque formation, which is a hallmark of neurodegenerative diseases.
  • Biomarker Studies: The compound is used in identifying and validating biomarkers for early diagnosis of Alzheimer's, helping in the design of more effective screening tests.
  • Peptide Synthesis: It is employed in solid-phase peptide synthesis, facilitating the creation of complex peptides for various biological applications, including vaccine development.
  • Cell Culture Experiments: This trifluoroacetate salt is utilized in cell culture studies to assess the effects of amyloid-beta on neuronal cells, providing insights into cellular responses and potential protective strategies.

Citations