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Catalog Number:
32911
CAS Number:
354151-60-3
Ac-Ala-Ser-Thr-Asp-AMC
Synonym(s):
Ac-ASTD-AMC
Documents
$249.07 /5MG
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Product Information

Ac-Ala-Ser-Thr-Asp-AMC is a synthetic peptide that serves as a valuable substrate for various biochemical assays, particularly in the field of proteomics and enzyme activity studies. This compound is recognized for its ability to facilitate the detection of proteolytic activity, making it an essential tool for researchers investigating enzyme kinetics and substrate specificity. Its unique structure, featuring multiple amino acids, allows for the mimicry of natural protein substrates, which enhances its utility in studying proteases and other enzymes involved in cellular processes.

In practical applications, Ac-Ala-Ser-Thr-Asp-AMC is widely used in drug discovery and development, particularly in screening for potential inhibitors of proteolytic enzymes that are implicated in various diseases, including cancer and neurodegenerative disorders. The compound's fluorescence properties enable real-time monitoring of enzyme activity, providing researchers with critical insights into the dynamics of proteolysis. With its robust performance and specificity, Ac-Ala-Ser-Thr-Asp-AMC stands out as a preferred choice for laboratories focused on advancing biochemical research and therapeutic innovations.

Synonyms
Ac-ASTD-AMC
CAS Number
354151-60-3
Molecular Formula
C26H33N5O11
Molecular Weight
591.58
MDL Number
MFCD02259618
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Ac-ASTD-AMC
CAS Number
354151-60-3
Molecular Formula
C26H33N5O11
Molecular Weight
591.58
MDL Number
MFCD02259618
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ac-Ala-Ser-Thr-Asp-AMC is widely utilized in research focused on:

  • Biochemical Assays: This compound serves as a substrate in enzyme activity assays, particularly for proteases. Its specific structure allows for the measurement of enzyme kinetics, providing valuable data for researchers studying enzyme functions.
  • Drug Development: In pharmaceutical research, it aids in the screening of potential drug candidates by mimicking peptide substrates. This helps in identifying compounds that can effectively inhibit or activate specific biological pathways.
  • Peptide Synthesis: This chemical is used in the synthesis of peptides for various applications, including therapeutic agents. Its stability and reactivity make it a preferred choice in peptide coupling reactions.
  • Fluorescent Labeling: The compound can be conjugated with fluorescent tags for imaging studies, allowing researchers to visualize cellular processes in real-time, which is crucial in cell biology and molecular research.
  • Diagnostics: It plays a role in developing diagnostic tools for diseases by serving as a marker in assays that detect specific proteins or enzymes associated with certain conditions, enhancing the accuracy of medical tests.

Citations