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Catalog Number:
32571
CAS Number:
1425938-65-3
Fmoc-(Dmb)Leu-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-N-(2,4-dimethoxybenzyl)-Leu-OH
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$72.31 /250MG
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Product Information

Fmoc-(Dmb)Leu-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a 2,4-dimethoxyphenyl group, enhances its stability and solubility, making it an excellent choice for researchers in the fields of medicinal chemistry and biochemistry.

In practical applications, Fmoc-(Dmb)Leu-OH is particularly valuable in solid-phase peptide synthesis (SPPS), where it facilitates the efficient assembly of complex peptide sequences. Its ability to provide high yields and purity levels makes it a preferred choice among professionals looking to develop therapeutic peptides or study protein interactions. Additionally, the compound's favorable properties allow for easy incorporation into various peptide libraries, paving the way for innovative drug discovery and development efforts.

Synonyms
Fmoc-N-(2,4-dimethoxybenzyl)-Leu-OH
CAS Number
1425938-65-3
Purity
≥ 98% (HPLC)
Molecular Formula
C30H33NO6
Molecular Weight
503.6
MDL Number
MFCD18643371
PubChem ID
139211114
Melting Point
58 - 60 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -31 ± 2 º (C=1 in DMF)
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Fmoc-N-(2,4-dimethoxybenzyl)-Leu-OH
CAS Number
1425938-65-3
Purity
≥ 98% (HPLC)
Molecular Formula
C30H33NO6
Molecular Weight
503.6
MDL Number
MFCD18643371
PubChem ID
139211114
Melting Point
58 - 60 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -31 ± 2 º (C=1 in DMF)
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(Dmb)Leu-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, allowing researchers to create specific sequences for various applications in drug development and biological research.
  • Drug Development: Its role in modifying amino acids makes it valuable in the design of novel therapeutics, particularly in the field of cancer treatment where targeted peptide drugs are being explored.
  • Bioconjugation: Fmoc-(Dmb)Leu-OH can be used to attach biomolecules to surfaces or other compounds, enhancing the functionality of drug delivery systems and diagnostic tools.
  • Research in Protein Engineering: This compound aids in the study of protein interactions and modifications, providing insights into enzyme activity and protein stability.
  • Custom Peptide Libraries: It is instrumental in creating diverse peptide libraries for screening potential drug candidates, allowing researchers to identify promising leads more efficiently.

Citations