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Catalog Number:
32567
CAS Number:
887707-95-1
Boc-Thr(Val-Fmoc)-OH
Purity:
≥ 98% (HPLC)
Antibiotic
Documents
$65.40 /250MG
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Product Information

Boc-Thr(Val-Fmoc)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique combination of protective groups, including the Fmoc (9-fluorenylmethyloxycarbonyl) and Boc (tert-butyloxycarbonyl) moieties, which facilitate selective reactions in complex peptide sequences. Its structure allows for the efficient incorporation of valine and threonine residues, making it an essential building block for researchers engaged in the synthesis of bioactive peptides and pharmaceuticals.

In the realm of medicinal chemistry, Boc-Thr(Val-Fmoc)-OH is particularly valuable for developing peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its stability under various reaction conditions and compatibility with standard coupling reagents enhance its appeal for both academic and industrial applications. Researchers can leverage this compound to streamline their synthesis processes, ultimately leading to more efficient drug discovery and development pathways.

CAS Number
887707-95-1
Purity
≥ 98% (HPLC)
Molecular Formula
C29H36N2O8
Molecular Weight
540.61
MDL Number
MFCD11974993
PubChem ID
73041743
Melting Point
88 - 97 ?C
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
General Information
CAS Number
887707-95-1
Purity
≥ 98% (HPLC)
Molecular Formula
C29H36N2O8
Molecular Weight
540.61
MDL Number
MFCD11974993
PubChem ID
73041743
Melting Point
88 - 97 ?C
Appearance
White to off-white powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Boc-Thr(Val-Fmoc)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective groups facilitate the selective addition of amino acids, allowing for complex peptide structures to be constructed efficiently.
  • Drug Development: In pharmaceutical research, Boc-Thr(Val-Fmoc)-OH is used to develop peptide-based drugs. Its unique structure can enhance the bioactivity and stability of therapeutic peptides, making it valuable in designing new medications.
  • Bioconjugation: The compound is employed in bioconjugation processes where it helps in attaching peptides to various biomolecules. This application is crucial in creating targeted drug delivery systems and improving the efficacy of therapeutic agents.
  • Protein Engineering: Researchers use this chemical in protein engineering to modify protein structures. By incorporating it into proteins, scientists can study the effects of specific amino acid changes on protein function and stability.
  • Academic Research: In academic settings, Boc-Thr(Val-Fmoc)-OH is frequently utilized in studies related to protein interactions and enzymatic functions. Its role in facilitating peptide synthesis makes it a staple in many biochemical laboratories.

Citations