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Catalog Number:
32544
CAS Number:
69975-86-6
Doxofylline
Purity:
≥ 98% (HPLC, AT)
Synonym(s):
7-(1,3-Dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione, 7-(1,3-Dioxolan-2-ylmethyl)theophylline
Documents
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Product Information

Doxofylline is a unique xanthine derivative known for its bronchodilator properties, making it a valuable compound in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Its mechanism of action involves the relaxation of bronchial smooth muscles, which helps to alleviate symptoms of airway obstruction. Doxofylline is particularly notable for its lower side effect profile compared to traditional theophylline, making it a preferred choice for patients who may experience adverse reactions to other bronchodilators.

In addition to its therapeutic applications, Doxofylline has been explored in research settings for its potential role in enhancing the efficacy of other medications and its anti-inflammatory properties. This compound is also being investigated for its use in combination therapies, which could lead to improved patient outcomes in managing chronic respiratory diseases. With its favorable pharmacokinetic profile and versatility, Doxofylline holds significant promise for both clinical and research applications.

Synonyms
7-(1,3-Dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione, 7-(1,3-Dioxolan-2-ylmethyl)theophylline
CAS Number
69975-86-6
Purity
≥ 98% (HPLC, AT)
Molecular Formula
C11H14N4O4
Molecular Weight
266.25
MDL Number
MFCD00865218
PubChem ID
50942
Melting Point
142 - 146 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
7-(1,3-Dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione, 7-(1,3-Dioxolan-2-ylmethyl)theophylline
CAS Number
69975-86-6
Purity
≥ 98% (HPLC, AT)
Molecular Formula
C11H14N4O4
Molecular Weight
266.25
MDL Number
MFCD00865218
PubChem ID
50942
Melting Point
142 - 146 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Doxofylline is widely utilized in research focused on

  • Respiratory Medicine: It is commonly used as a bronchodilator to treat conditions like asthma and chronic obstructive pulmonary disease (COPD), providing relief by relaxing the airways.
  • Pharmaceutical Formulations: Doxofylline is incorporated into various drug formulations, enhancing the efficacy of respiratory medications and improving patient compliance due to its favorable side effect profile.
  • Clinical Research: Researchers study its pharmacokinetics and pharmacodynamics to optimize dosing regimens and improve therapeutic outcomes in respiratory diseases.
  • Combination Therapies: It is often used in combination with other medications to enhance bronchodilation effects, making it a valuable option for patients with severe symptoms.
  • Patient-Centric Approaches: Doxofylline's unique mechanism of action allows for better management of symptoms with fewer side effects compared to traditional xanthine derivatives, addressing patient concerns effectively.

Citations