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Catalog Number:
32507
CAS Number:
148-72-1
Pilocarpine nitrate salt
Purity:
≥ 98% (HPLC)
Synonym(s):
(3S,4R)-4,5-Dihydro-3-ethyl-4-(1-methyl-1H-imidazol-5-ylmethyl)-2(3H)-furanone nitrate, 3-Ethyl-4-[(1-methyl-5-imidazolyl)methyl]tetrahydrofuran-2-one nitrate
Hazmat
Documents
$70.00 /1G
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Product Information

Pilocarpine nitrate salt is a potent alkaloid known for its significant role in medical applications, particularly in the treatment of glaucoma and dry mouth conditions. This compound acts as a muscarinic agonist, stimulating the secretion of saliva and enhancing ocular fluid drainage, which is crucial for managing intraocular pressure. Its effectiveness in promoting salivation makes it invaluable for patients suffering from xerostomia, often resulting from medications or certain medical conditions.

In addition to its therapeutic uses, pilocarpine nitrate salt is also utilized in research settings to study cholinergic signaling pathways and their implications in various physiological processes. The compound's unique structure allows for targeted interactions within biological systems, making it a valuable tool for pharmacological studies. With its established efficacy and diverse applications, pilocarpine nitrate salt remains a critical resource for both healthcare professionals and researchers seeking innovative solutions in their respective fields.

Synonyms
(3S,4R)-4,5-Dihydro-3-ethyl-4-(1-methyl-1H-imidazol-5-ylmethyl)-2(3H)-furanone nitrate, 3-Ethyl-4-[(1-methyl-5-imidazolyl)methyl]tetrahydrofuran-2-one nitrate
CAS Number
148-72-1
Purity
≥ 98% (HPLC)
Molecular Formula
C11H16N2O2·HNO3
Molecular Weight
271.27
MDL Number
MFCD00078497
PubChem ID
18529172
Melting Point
173 - 174 ?C (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = 77 - 83 ° (C = 10 in Water)
Conditions
Store at RT
General Information
Synonyms
(3S,4R)-4,5-Dihydro-3-ethyl-4-(1-methyl-1H-imidazol-5-ylmethyl)-2(3H)-furanone nitrate, 3-Ethyl-4-[(1-methyl-5-imidazolyl)methyl]tetrahydrofuran-2-one nitrate
CAS Number
148-72-1
Purity
≥ 98% (HPLC)
Molecular Formula
C11H16N2O2·HNO3
Molecular Weight
271.27
MDL Number
MFCD00078497
PubChem ID
18529172
Melting Point
173 - 174 ?C (Lit.)
Appearance
White powder
Optical Rotation
[a]D20 = 77 - 83 ° (C = 10 in Water)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pilocarpine nitrate salt is widely utilized in research focused on

  • Ophthalmology: It is commonly used to treat glaucoma by reducing intraocular pressure, making it essential in eye care treatments.
  • Salivary Stimulation: This compound is effective in stimulating saliva production in patients with dry mouth conditions, such as those undergoing cancer therapy.
  • Neurological Research: Pilocarpine is used in studies related to epilepsy and neurodegenerative diseases, helping researchers understand seizure mechanisms.
  • Pharmaceutical Formulations: It serves as an active ingredient in various medications, providing targeted therapeutic effects in formulations for specific health conditions.
  • Veterinary Medicine: The compound is also applied in veterinary practices to manage certain conditions in animals, showcasing its versatility beyond human medicine.

Citations