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Catalog Number:
32505
CAS Number:
61-76-7
R-(-)-Phenylephrine hydrochloride
Grade:
meets USP specifications
Purity:
98 - 102% (Assay, on dry basis)
Synonym(s):
(R-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanolhydrochloride, (R-(-)-3-Hydroxy-α-(methylaminomethyl)benzyl alcoholhydrochloride
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Product Information

(R)-(-)-Phenylephrine hydrochloride is a potent sympathomimetic agent widely utilized in the pharmaceutical industry, primarily for its vasoconstrictive properties. This compound is recognized for its effectiveness in treating nasal congestion and hypotension, making it a valuable ingredient in various over-the-counter decongestants and prescription medications. Its ability to selectively stimulate alpha-1 adrenergic receptors leads to increased vascular resistance and reduced nasal mucosal swelling, providing relief for patients suffering from colds, allergies, or sinus infections.

In addition to its applications in respiratory therapies, (R)-(-)-Phenylephrine hydrochloride is also employed in ophthalmology to induce mydriasis during eye examinations. Its rapid onset and relatively short duration of action make it an ideal choice for healthcare professionals seeking effective solutions for patient care. With a favorable safety profile and a well-established history of use, this compound stands out as a reliable option for both researchers and practitioners looking to enhance therapeutic outcomes in their respective fields.

Synonyms
(R-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanolhydrochloride, (R-(-)-3-Hydroxy-α-(methylaminomethyl)benzyl alcoholhydrochloride
CAS Number
61-76-7
Purity
98 - 102% (Assay, on dry basis)
Grade
meets USP specifications
Molecular Formula
C9H13NO2·HCl
Molecular Weight
203.67
MDL Number
MFCD00012605
PubChem ID
6102
Melting Point
143-145 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = -43 to -47 °
Conditions
Store at RT
General Information
Synonyms
(R-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanolhydrochloride, (R-(-)-3-Hydroxy-α-(methylaminomethyl)benzyl alcoholhydrochloride
CAS Number
61-76-7
Purity
98 - 102% (Assay, on dry basis)
Grade
meets USP specifications
Molecular Formula
C9H13NO2·HCl
Molecular Weight
203.67
MDL Number
MFCD00012605
PubChem ID
6102
Melting Point
143-145 °C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = -43 to -47 °
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(-)-Phenylephrine hydrochloride is widely utilized in research focused on

  • Pharmaceutical Formulations: Commonly used as a decongestant in cold and allergy medications, it helps relieve nasal congestion by constricting blood vessels in the nasal passages.
  • Ophthalmic Solutions: Employed in eye drops to dilate pupils during eye examinations, providing clear visibility for healthcare professionals.
  • Cardiovascular Research: Utilized in studies examining blood pressure regulation and vascular responses, aiding researchers in understanding cardiovascular health.
  • Veterinary Medicine: Applied in veterinary practices for treating certain conditions in animals, showcasing its versatility beyond human medicine.
  • Clinical Trials: Frequently involved in clinical studies assessing its efficacy and safety, contributing to the development of new therapeutic strategies.

Citations