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Catalog Number:
32501
CAS Number:
912-60-7
Noscapine hydrochloride hydrate
Purity:
≥ 98%(HPLC,T)
Synonym(s):
Narcotine hydrochloride hydrate
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Product Information

Noscapine hydrochloride hydrate is a versatile compound recognized for its significant applications in both pharmaceutical research and therapeutic settings. As a naturally occurring alkaloid derived from the opium poppy, it is primarily known for its antitussive properties, making it an effective cough suppressant. Researchers are increasingly exploring its potential in cancer treatment due to its ability to inhibit cell division by disrupting microtubule formation, which can enhance the efficacy of certain chemotherapeutic agents. Additionally, its low toxicity profile compared to traditional opioids presents a safer alternative for pain management, particularly in patients who may be sensitive to conventional narcotics.

This compound's unique structure allows for various modifications, leading to the development of novel derivatives with improved pharmacological properties. Its applications extend to the formulation of innovative drug delivery systems, where it can serve as a key ingredient in creating targeted therapies. With ongoing studies highlighting its potential in treating a range of conditions, including respiratory issues and cancer, noscapine hydrochloride hydrate stands out as a promising candidate for further exploration in modern medicine.

Synonyms
Narcotine hydrochloride hydrate
CAS Number
912-60-7
Purity
≥ 98%(HPLC,T)
Molecular Formula
C22H23NO7·HCl·H2O
Molecular Weight
467.9
MDL Number
MFCD00149223
PubChem ID
657273
Melting Point
200 °C
Appearance
White to almost white crystalline powder
Optical Rotation
[a]20/D= +43 to +47° (C=0.5 in 0.1mol/L HCl, calcd.on anh.substance)
Conditions
Store at RT
General Information
Synonyms
Narcotine hydrochloride hydrate
CAS Number
912-60-7
Purity
≥ 98%(HPLC,T)
Molecular Formula
C22H23NO7·HCl·H2O
Molecular Weight
467.9
MDL Number
MFCD00149223
PubChem ID
657273
Melting Point
200 °C
Appearance
White to almost white crystalline powder
Optical Rotation
[a]20/D= +43 to +47° (C=0.5 in 0.1mol/L HCl, calcd.on anh.substance)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Noscapine hydrochloride hydrate is widely utilized in research focused on:

  • Cancer Treatment: This compound has shown promise as a potential anti-cancer agent. Researchers are exploring its ability to inhibit tumor growth and metastasis, making it a candidate for developing new cancer therapies.
  • Antitussive Applications: Known for its cough-suppressing properties, noscapine is used in the formulation of cough syrups and medications, providing relief without the sedative effects commonly associated with other cough suppressants.
  • Neuroscience Research: It is being studied for its effects on the central nervous system, particularly in understanding pain pathways and potential applications in pain management therapies.
  • Pharmaceutical Development: As a versatile compound, it serves as a lead structure for synthesizing new drugs, allowing pharmaceutical companies to innovate and improve existing treatments.
  • Natural Product Chemistry: Noscapine is derived from opium poppy, making it a subject of interest in studies related to natural products and their therapeutic potentials, highlighting its role in sustainable drug development.

Citations