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7-Ethylcamptothecin
7-Ethylcamptothecin is widely utilized in research focused on:
- Cancer Treatment: This compound is a potent inhibitor of topoisomerase I, making it a valuable candidate in the development of anti-cancer therapies. It has shown promising results in clinical trials for various cancers, including colorectal and lung cancer.
- Pharmaceutical Development: Researchers are exploring its potential in formulating new drugs that can overcome resistance seen with traditional chemotherapy agents. Its unique structure allows for modifications that can enhance efficacy and reduce side effects.
- Drug Delivery Systems: Due to its hydrophobic nature, 7-Ethylcamptothecin can be incorporated into nanocarriers for targeted drug delivery, improving the concentration of the drug at tumor sites while minimizing systemic exposure.
- Research on Mechanisms of Action: Scientists use this compound to study the mechanisms of DNA damage and repair, providing insights into cellular responses to chemotherapy and helping to identify biomarkers for treatment efficacy.
- Combination Therapies: It is being investigated in combination with other therapeutic agents to enhance overall treatment outcomes, particularly in resistant cancer types, showcasing its versatility in oncology.
General Information
Properties
Safety and Regulations
Applications
7-Ethylcamptothecin is widely utilized in research focused on:
- Cancer Treatment: This compound is a potent inhibitor of topoisomerase I, making it a valuable candidate in the development of anti-cancer therapies. It has shown promising results in clinical trials for various cancers, including colorectal and lung cancer.
- Pharmaceutical Development: Researchers are exploring its potential in formulating new drugs that can overcome resistance seen with traditional chemotherapy agents. Its unique structure allows for modifications that can enhance efficacy and reduce side effects.
- Drug Delivery Systems: Due to its hydrophobic nature, 7-Ethylcamptothecin can be incorporated into nanocarriers for targeted drug delivery, improving the concentration of the drug at tumor sites while minimizing systemic exposure.
- Research on Mechanisms of Action: Scientists use this compound to study the mechanisms of DNA damage and repair, providing insights into cellular responses to chemotherapy and helping to identify biomarkers for treatment efficacy.
- Combination Therapies: It is being investigated in combination with other therapeutic agents to enhance overall treatment outcomes, particularly in resistant cancer types, showcasing its versatility in oncology.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.