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Catalog Number:
32466
CAS Number:
6190-39-2
Dihydroergotamine methanesulfonate salt
Purity:
≥ 99% (HPLC)
Synonym(s):
Dihydroergotamine Mesylate
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$88.63 /100MG
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Product Information

Dihydroergotamine methanesulfonate salt is a potent pharmaceutical compound primarily utilized in the treatment of acute migraine attacks and cluster headaches. This compound acts as a selective agonist for serotonin receptors, which plays a crucial role in alleviating headache symptoms by constricting dilated blood vessels in the brain. Its unique formulation enhances solubility and bioavailability, making it an effective choice for both intravenous and intranasal administration.

In addition to its primary use in headache management, dihydroergotamine methanesulfonate salt has shown potential in various research applications, including studies on vascular disorders and the modulation of neurotransmitter systems. Its ability to provide rapid relief makes it a preferred option among healthcare professionals for patients who require immediate intervention. With its established efficacy and safety profile, this compound stands out in the pharmaceutical landscape, offering significant advantages over other migraine treatments, particularly in terms of onset of action and patient tolerance.

Synonyms
Dihydroergotamine Mesylate
CAS Number
6190-39-2
Purity
≥ 99% (HPLC)
Molecular Formula
C33H37N5O5·CH4O3S
Molecular Weight
679.78
MDL Number
MFCD00058615
PubChem ID
517557
Melting Point
230 - 235 °C
Appearance
White to light yellow to light red powder to crystal
Optical Rotation
[a]D20 = -17 to -23 ° (C=0.25, JP Method) (calcd. on dried substance)
Conditions
Store at RT
General Information
Synonyms
Dihydroergotamine Mesylate
CAS Number
6190-39-2
Purity
≥ 99% (HPLC)
Molecular Formula
C33H37N5O5·CH4O3S
Molecular Weight
679.78
MDL Number
MFCD00058615
PubChem ID
517557
Melting Point
230 - 235 °C
Appearance
White to light yellow to light red powder to crystal
Optical Rotation
[a]D20 = -17 to -23 ° (C=0.25, JP Method) (calcd. on dried substance)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dihydroergotamine methanesulfonate salt is widely utilized in research focused on:

  • Migraine Treatment: This compound is primarily used in the medical field to treat acute migraine attacks. It works by constricting blood vessels in the brain, providing relief to patients who suffer from severe headaches.
  • Vascular Research: In pharmacological studies, it serves as a model compound for understanding vascular responses. Researchers can explore its effects on blood flow and vascular tone, aiding in the development of new cardiovascular therapies.
  • Pharmaceutical Development: The compound is often used in the formulation of medications, allowing scientists to study its stability and efficacy in various delivery systems, such as intranasal or injectable forms.
  • Neuropharmacology: It is utilized in neuropharmacological research to investigate its interactions with serotonin receptors, contributing to the understanding of neurotransmitter systems and potential treatments for other neurological disorders.
  • Clinical Trials: Dihydroergotamine methanesulfonate salt is frequently involved in clinical trials aimed at assessing new therapeutic strategies for migraine and other headache disorders, providing valuable data for future drug approvals.

Citations