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Catalog Number:
32454
CAS Number:
24302-67-8
Cinchonidine dihydrochloride
Purity:
≥ 98% (AT)
Synonym(s):
(-)-Cinchonidine dihydrochloride
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Product Information

Cinchonidine dihydrochloride is a versatile compound known for its significant role in the pharmaceutical industry, particularly in the synthesis of various alkaloids and as a chiral auxiliary in asymmetric synthesis. This compound, a derivative of cinchonidine, exhibits unique properties that make it invaluable in the development of enantiomerically pure compounds, which are crucial in drug formulation and development. Its ability to facilitate the resolution of racemic mixtures enhances its appeal to researchers and industry professionals focused on producing high-purity pharmaceuticals.

In addition to its applications in organic synthesis, cinchonidine dihydrochloride is also recognized for its potential use in the treatment of malaria and other parasitic infections, owing to its structural similarity to quinine. This compound's effectiveness in various chemical reactions, combined with its relatively straightforward synthesis, positions it as a preferred choice for researchers seeking reliable and efficient solutions in drug discovery and development. Its unique features, such as high solubility and stability, further enhance its utility in laboratory settings, making it an essential addition to any chemist's toolkit.

Synonyms
(-)-Cinchonidine dihydrochloride
CAS Number
24302-67-8
Purity
≥ 98% (AT)
Molecular Formula
C19H22N2O·2HCl
Molecular Weight
367.31
MDL Number
MFCD00082451
PubChem ID
18625690
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20/D = -140 to -150 ° (C = 0.4 in H2O)
Conditions
Store at RT
General Information
Synonyms
(-)-Cinchonidine dihydrochloride
CAS Number
24302-67-8
Purity
≥ 98% (AT)
Molecular Formula
C19H22N2O·2HCl
Molecular Weight
367.31
MDL Number
MFCD00082451
PubChem ID
18625690
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20/D = -140 to -150 ° (C = 0.4 in H2O)
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cinchonidine dihydrochloride is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various alkaloids, which are essential for developing new medications, particularly in treating cardiovascular diseases.
  • Chiral Catalysis: It is employed as a chiral ligand in asymmetric synthesis, helping chemists create molecules with specific orientations, which is crucial in producing effective drugs with fewer side effects.
  • Analytical Chemistry: Cinchonidine dihydrochloride is used in chiral chromatography for separating enantiomers, allowing researchers to analyze the purity and composition of pharmaceutical compounds.
  • Natural Product Research: This compound is often used in studies involving natural products, aiding in the extraction and identification of bioactive compounds from plant sources.
  • Teaching and Education: Its unique properties make it a valuable tool in educational settings for demonstrating concepts in organic chemistry and stereochemistry, enhancing students' understanding of complex chemical interactions.

Citations