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Catalog Number:
32440
CAS Number:
5908-99-6
Atropine sulfate salt monohydrate
Purity:
98 - 102% (Assay)
Synonym(s):
α-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate, Tropine tropate
Hazmat
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Product Information

Atropine sulfate salt monohydrate is a well-known alkaloid with significant applications in both medical and research fields. This compound is primarily utilized as a medication to treat bradycardia, reduce salivation during surgery, and as an antidote for certain types of poisoning. Its ability to block the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands, and the central nervous system makes it invaluable in various therapeutic contexts. Researchers also leverage atropine sulfate in pharmacological studies to explore its effects on the nervous system, enhancing our understanding of neurotransmitter interactions.

In addition to its medicinal uses, atropine sulfate salt monohydrate serves as a critical tool in the development of anticholinergic agents and is often employed in the synthesis of other chemical compounds. Its unique properties, such as its solubility and stability, make it a preferred choice for pharmaceutical formulations. The compound's versatility and effectiveness in diverse applications underscore its importance in both clinical and laboratory settings, providing significant benefits to healthcare professionals and researchers alike.

Synonyms
α-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate, Tropine tropate
CAS Number
5908-99-6
Purity
98 - 102% (Assay)
Molecular Formula
C34H46N2O6·H2SO4·H2O
Molecular Weight
694.84
MDL Number
MFCD00074815
PubChem ID
64663
Melting Point
189-192 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = -0.5 to +0.05 °
Conditions
Store at 2-8 °C
General Information
Synonyms
α-(Hydroxymethyl)benzeneacetic acid (3-endo)-8- methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate, Tropine tropate
CAS Number
5908-99-6
Purity
98 - 102% (Assay)
Molecular Formula
C34H46N2O6·H2SO4·H2O
Molecular Weight
694.84
MDL Number
MFCD00074815
PubChem ID
64663
Melting Point
189-192 °C
Appearance
White crystalline powder
Optical Rotation
[a]20D = -0.5 to +0.05 °
Conditions
Store at 2-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Atropine sulfate salt monohydrate is widely utilized in research focused on:

  • Medical Applications: It is commonly used in emergency medicine to treat bradycardia (slow heart rate) and to reduce salivation during surgery, enhancing patient comfort and safety.
  • Ophthalmology: The compound is employed as a mydriatic agent to dilate pupils during eye examinations, allowing for better visualization of the retina and other internal structures.
  • Neurological Research: Researchers utilize atropine sulfate in studies related to neurotransmission and the effects of anticholinergic drugs, aiding in the understanding of various neurological disorders.
  • Antidote for Poisoning: It serves as an antidote for organophosphate poisoning, which is crucial in agricultural and environmental health sectors, providing rapid intervention in toxic exposure cases.
  • Pharmaceutical Formulations: The compound is often incorporated into various formulations for its antispasmodic properties, helping to relieve muscle spasms in gastrointestinal and urinary tract disorders.

Citations