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Catalog Number:
32381
CAS Number:
73346-74-4
-)-2,3-O-Isopropylidene-D-threitol
Purity:
≥ 98% (GC)
Synonym(s):
(4R,5R-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol, (4R,5R-(-)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane
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Product Information

(-)-2,3-O-Isopropylidene-D-threitol is a versatile chemical compound recognized for its unique structural properties and functional applications in various fields. This compound, also known as D-threitol 2,3-isopropylidene acetal, serves as an important intermediate in organic synthesis, particularly in the production of carbohydrates and glycosides. Its ability to protect hydroxyl groups makes it invaluable in synthetic chemistry, allowing for selective reactions that enhance yield and purity.

In the pharmaceutical industry, (-)-2,3-O-Isopropylidene-D-threitol is utilized in the synthesis of complex molecules, contributing to the development of new drugs and therapeutic agents. Additionally, its role in carbohydrate chemistry opens avenues for research in glycoproteins and polysaccharides, making it a crucial component for researchers focused on biochemistry and molecular biology. With its favorable properties and applications, this compound stands out as a key player in advancing scientific research and industrial processes.

Synonyms
(4R,5R-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol, (4R,5R-(-)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane
CAS Number
73346-74-4
Purity
≥ 98% (GC)
Molecular Formula
C7H14O4
Molecular Weight
162.19
MDL Number
MFCD00009761
PubChem ID
318275
Melting Point
47-52° C
Appearance
White to off-white crystalline powder
Boiling Point
88-90° C / 0.05mmHg
Optical Rotation
[a]20/D= -3 to -5° (C=5 in Aceton)
Conditions
Store at ≤ -10 °C
General Information
Synonyms
(4R,5R-2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol, (4R,5R-(-)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane
CAS Number
73346-74-4
Purity
≥ 98% (GC)
Molecular Formula
C7H14O4
Molecular Weight
162.19
MDL Number
MFCD00009761
PubChem ID
318275
Melting Point
47-52° C
Appearance
White to off-white crystalline powder
Boiling Point
88-90° C / 0.05mmHg
Optical Rotation
[a]20/D= -3 to -5° (C=5 in Aceton)
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(-)-2,3-O-Isopropylidene-D-threitol is widely utilized in research focused on:

  • Synthesis of Carbohydrate Derivatives: This compound serves as a key intermediate in the synthesis of various carbohydrate derivatives, which are essential in the development of pharmaceuticals and glycosylation reactions.
  • Protecting Group in Organic Chemistry: It acts as an effective protecting group for hydroxyl functionalities during multi-step organic synthesis, enhancing the yield and purity of final products.
  • Research in Glycobiology: The compound is valuable in glycobiology studies, aiding in the exploration of glycan structures and their biological functions, which can lead to advancements in drug development.
  • Development of Antiviral Agents: Its derivatives have shown potential in the formulation of antiviral agents, contributing to the fight against viral infections by modifying sugar moieties.
  • Biochemical Applications: Used in the preparation of various biochemical probes, it helps researchers study enzyme activities and interactions, providing insights into metabolic pathways.

Citations