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Catalog Number:
32375
CAS Number:
37002-45-2
(-)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol
Purity:
≥ 97% (HPLC)
Synonym(s):
(-)-2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol, (-)-2,3-O-Isopropylidene-L-threitol 1,4-ditosylate
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Product Information

(-)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol is a versatile chemical compound widely utilized in organic synthesis and medicinal chemistry. This compound serves as a valuable intermediate in the preparation of various glycosides and other complex organic molecules. Its unique structure, featuring two tosyl groups, enhances its reactivity, making it an excellent choice for chemists looking to develop new synthetic pathways. Researchers appreciate its role in facilitating the formation of glycosidic bonds, which are crucial in the synthesis of carbohydrates and related compounds.

In addition to its applications in synthetic chemistry, (-)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol is also explored for its potential in pharmaceutical development, particularly in the design of antiviral and anticancer agents. Its ability to act as a protecting group for hydroxyl functionalities allows for selective reactions, streamlining complex synthetic routes. This compound stands out for its efficiency and effectiveness in various applications, making it a preferred choice for professionals in both research and industrial settings.

Synonyms
(-)-2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol, (-)-2,3-O-Isopropylidene-L-threitol 1,4-ditosylate
CAS Number
37002-45-2
Purity
≥ 97% (HPLC)
Molecular Formula
C21H26O8S2
Molecular Weight
470.56
MDL Number
MFCD00003212
PubChem ID
275953
Melting Point
90 - 92 °C
Appearance
Off-white solid
Optical Rotation
[a]D20 = -13 ± 1 ° (C=8.8 in Chloroform)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(-)-2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol, (-)-2,3-O-Isopropylidene-L-threitol 1,4-ditosylate
CAS Number
37002-45-2
Purity
≥ 97% (HPLC)
Molecular Formula
C21H26O8S2
Molecular Weight
470.56
MDL Number
MFCD00003212
PubChem ID
275953
Melting Point
90 - 92 °C
Appearance
Off-white solid
Optical Rotation
[a]D20 = -13 ± 1 ° (C=8.8 in Chloroform)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(-)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol is widely utilized in research focused on:

  • Synthetic Organic Chemistry: This compound serves as a versatile intermediate in the synthesis of complex organic molecules, facilitating the creation of various pharmaceuticals and agrochemicals.
  • Chiral Auxiliary Applications: It is employed as a chiral auxiliary in asymmetric synthesis, helping researchers produce enantiomerically pure compounds more efficiently, which is crucial in drug development.
  • Bioconjugation Techniques: The compound is useful in bioconjugation processes, allowing for the attachment of biomolecules to surfaces or other molecules, enhancing the effectiveness of drug delivery systems.
  • Research in Glycochemistry: It plays a role in the synthesis of glycosides and other carbohydrate derivatives, essential for studying biological processes and developing carbohydrate-based drugs.
  • Analytical Chemistry: This chemical is used in the development of analytical methods for detecting and quantifying specific compounds, aiding in quality control and research applications.

Citations