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Catalog Number:
32311
CAS Number:
71484-85-0
4-Nitrophenyl α-D-Glucuronide
Purity:
≥ 97% (HPLC)
Synonym(s):
4-Nitrophenyl α-D-glucopyranosiduronic acid
Documents
$110.70 /5MG
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Product Information

4-Nitrophenyl a-D-Glucuronide is a valuable compound widely utilized in biochemical research and pharmaceutical applications. This compound serves as a substrate for various glucuronidation studies, allowing researchers to investigate the metabolic pathways of drugs and other xenobiotics. Its ability to mimic natural substrates makes it an essential tool for studying enzyme activity, particularly in the context of drug metabolism and detoxification processes.

Additionally, 4-Nitrophenyl a-D-Glucuronide is recognized for its role in the development of assays that measure glucuronidation activity, which is crucial in pharmacokinetics and toxicology. By providing insights into the conjugation reactions that occur in the liver, this compound aids in understanding individual variations in drug response and potential adverse effects. Its unique properties make it a preferred choice for researchers looking to enhance the accuracy and efficiency of their studies in drug metabolism.

Synonyms
4-Nitrophenyl α-D-glucopyranosiduronic acid
CAS Number
71484-85-0
Purity
≥ 97% (HPLC)
Molecular Formula
C12H13NO9
Molecular Weight
315.23
MDL Number
MFCD15072186
PubChem ID
3291162
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]D20 = 163 - 167 ° (C = 0.7 in EtOH)
Conditions
Store at ≤ -10 °C
General Information
Synonyms
4-Nitrophenyl α-D-glucopyranosiduronic acid
CAS Number
71484-85-0
Purity
≥ 97% (HPLC)
Molecular Formula
C12H13NO9
Molecular Weight
315.23
MDL Number
MFCD15072186
PubChem ID
3291162
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]D20 = 163 - 167 ° (C = 0.7 in EtOH)
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Nitrophenyl a-D-Glucuronide is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate in assays to measure the activity of glucuronidase enzymes, which are important in drug metabolism studies.
  • Drug Development: It plays a crucial role in pharmacokinetics research, helping scientists understand how drugs are processed in the body, particularly in relation to conjugation reactions.
  • Toxicology Studies: Researchers use it to evaluate the detoxification pathways of various compounds, aiding in the assessment of potential toxic effects of new drugs or environmental chemicals.
  • Biochemical Research: It is employed in studies investigating the role of glucuronidation in various biological processes, contributing to a better understanding of metabolic pathways.
  • Clinical Diagnostics: This compound can be used in the development of diagnostic tests to measure glucuronidase levels in biological samples, providing insights into certain diseases and conditions.

Citations