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Catalog Number:
31984
CAS Number:
147081-44-5
(S)-(-)-1-Boc-3-aminopyrrolidine
Purity:
≥ 99% (Chiral purity)
Synonym(s):
(S)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine
Hazmat
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Product Information

(S)-(-)-1-Boc-3-aminopyrrolidine is a versatile compound widely utilized in the synthesis of various pharmaceuticals and agrochemicals. This chiral building block is particularly valued in medicinal chemistry for its role in the development of biologically active molecules, including potential drug candidates. Its unique structure allows for the introduction of amine functionalities, making it an essential intermediate in the preparation of complex organic compounds. Researchers appreciate its stability and ease of handling, which facilitate efficient reactions in both academic and industrial settings.

In addition to its applications in drug discovery, (S)-(-)-1-Boc-3-aminopyrrolidine is also employed in the synthesis of peptide-based therapeutics and as a chiral auxiliary in asymmetric synthesis. Its ability to enhance selectivity in reactions makes it a preferred choice for chemists aiming to optimize yields and purity. With its growing importance in the pharmaceutical industry, this compound stands out for its potential to contribute to innovative solutions in drug development and other chemical applications.

Synonyms
(S)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine
CAS Number
147081-44-5
Purity
≥ 99% (Chiral purity)
Molecular Formula
C9H18N2O2
Molecular Weight
186.25
MDL Number
MFCD03419271
PubChem ID
2756370
Density
1.07
Appearance
Light yellow to colorless liquid
Boiling Point
95 - 98 °C / 5mm Hg
Optical Rotation
[a]20D = -1.8 to -3.5 ° (C= 2.5% in CHCl3)
Conditions
Store at RT
General Information
Synonyms
(S)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine
CAS Number
147081-44-5
Purity
≥ 99% (Chiral purity)
Molecular Formula
C9H18N2O2
Molecular Weight
186.25
MDL Number
MFCD03419271
PubChem ID
2756370
Density
1.07
Appearance
Light yellow to colorless liquid
Boiling Point
95 - 98 °C / 5mm Hg
Optical Rotation
[a]20D = -1.8 to -3.5 ° (C= 2.5% in CHCl3)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-1-Boc-3-aminopyrrolidine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is employed in the preparation of peptide-based therapeutics, enhancing the stability and bioavailability of peptide drugs.
  • Chiral Building Blocks: As a chiral building block, it is crucial in asymmetric synthesis, allowing chemists to create compounds with specific stereochemistry for improved efficacy.
  • Research in Organic Chemistry: It is used in organic synthesis research, helping to develop new methodologies for creating complex organic molecules.
  • Material Science: The compound finds applications in the development of new materials, including polymers and coatings, due to its unique chemical properties.

Citations