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Catalog Number:
31983
CAS Number:
147081-49-0
(R)-(+)-1-Boc-3-aminopyrrolidine
Purity:
≥ 97% (Assay)
Synonym(s):
(R)-(+)-N-Boc-3-aminopyrrolidine, (R)-(+)-1-tert-Butoxycarbonyl-3-aminopyrrolidine
Hazmat
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Product Information

(R)-(+)-1-Boc-3-aminopyrrolidine is a valuable chiral building block widely utilized in the synthesis of pharmaceuticals and agrochemicals. This compound features a tert-butyl carbamate protecting group, which enhances its stability and solubility, making it an ideal candidate for various chemical reactions. Its unique structure allows for the introduction of amino functionalities, which are crucial in the development of biologically active molecules. Researchers often leverage this compound in asymmetric synthesis, particularly in the creation of complex natural products and drug candidates, where chirality plays a significant role in biological activity.

In addition to its applications in medicinal chemistry, (R)-(+)-1-Boc-3-aminopyrrolidine is also employed in the production of peptide-based therapeutics and in the development of novel materials. Its ability to facilitate the formation of diverse molecular architectures makes it an essential tool for chemists aiming to innovate in drug design and development. With its proven effectiveness and versatility, this compound stands out as a preferred choice for professionals seeking reliable and efficient solutions in their research and development projects.

Synonyms
(R)-(+)-N-Boc-3-aminopyrrolidine, (R)-(+)-1-tert-Butoxycarbonyl-3-aminopyrrolidine
CAS Number
147081-49-0
Purity
≥ 97% (Assay)
Molecular Formula
C9H18N2O2
Molecular Weight
186.25
MDL Number
MFCD03419272
PubChem ID
2756370
Density
1.10 (Lit.)
Appearance
Light yellow to colorless liquid
Boiling Point
95 - 98 ?C / 5mm Hg (Lit.)
Optical Rotation
[a]D20 = 3 - 4 °
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(R)-(+)-N-Boc-3-aminopyrrolidine, (R)-(+)-1-tert-Butoxycarbonyl-3-aminopyrrolidine
CAS Number
147081-49-0
Purity
≥ 97% (Assay)
Molecular Formula
C9H18N2O2
Molecular Weight
186.25
MDL Number
MFCD03419272
PubChem ID
2756370
Density
1.10 (Lit.)
Appearance
Light yellow to colorless liquid
Boiling Point
95 - 98 ?C / 5mm Hg (Lit.)
Optical Rotation
[a]D20 = 3 - 4 °
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(+)-1-Boc-3-aminopyrrolidine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Organic Synthesis: It is employed in organic synthesis as a chiral building block, allowing chemists to create complex molecules with specific stereochemistry, which is crucial for drug efficacy.
  • Biochemical Research: Researchers use this compound to study enzyme interactions and protein folding, contributing to a better understanding of biological processes.
  • Material Science: Its unique properties make it useful in developing new materials, particularly in creating polymers that require specific functional groups for enhanced performance.
  • Analytical Chemistry: This chemical is utilized in analytical methods to detect and quantify other compounds, providing valuable data for quality control in various industries.

Citations