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Catalog Number:
31982
CAS Number:
81290-20-2
Trifluoromethyl)trimethylsilane, 0.5M soln. in THF
Purity:
0.45 - 0.6 M (Assay)
Synonym(s):
Trimethyl(trifluoromethyl)silane solution, Ruppert's reagent
Hazmat
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$22.03 /5ML
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Product Information

(Trifluoromethyl)trimethylsilane is a versatile organosilicon compound that plays a crucial role in various chemical applications, particularly in the synthesis of fluorinated compounds. This compound is recognized for its unique trifluoromethyl group, which enhances the reactivity and stability of the resulting products. It is commonly utilized in the development of pharmaceuticals, agrochemicals, and specialty chemicals, where the incorporation of fluorine can significantly improve the biological activity and metabolic stability of the molecules.

In research and industrial settings, (Trifluoromethyl)trimethylsilane serves as a valuable reagent for introducing trifluoromethyl groups into organic substrates, facilitating the creation of novel compounds with desirable properties. Its solubility in tetrahydrofuran (THF) allows for easy handling and integration into various reaction conditions. This compound stands out for its ability to enhance the performance of materials and products in fields such as medicinal chemistry and materials science, making it an essential tool for researchers and industry professionals looking to innovate and improve their formulations.

Synonyms
Trimethyl(trifluoromethyl)silane solution, Ruppert's reagent
CAS Number
81290-20-2
Purity
0.45 - 0.6 M (Assay)
Molecular Formula
C4H9F3Si
Molecular Weight
142.19
MDL Number
MFCD00145454
PubChem ID
552549
Density
0.895
Appearance
Colorless liquid
Boiling Point
40 ?C
Conditions
Store at RT
General Information
Synonyms
Trimethyl(trifluoromethyl)silane solution, Ruppert's reagent
CAS Number
81290-20-2
Purity
0.45 - 0.6 M (Assay)
Molecular Formula
C4H9F3Si
Molecular Weight
142.19
MDL Number
MFCD00145454
PubChem ID
552549
Density
0.895
Appearance
Colorless liquid
Boiling Point
40 ?C
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(Trifluoromethyl)trimethylsilane is widely utilized in research focused on:

  • Synthetic Chemistry: This compound serves as a valuable reagent in organic synthesis, particularly for introducing trifluoromethyl groups into various organic molecules, enhancing their biological activity and stability.
  • Pharmaceutical Development: It plays a crucial role in the development of new pharmaceuticals, where trifluoromethylation can improve drug efficacy and reduce metabolic degradation, making compounds more effective.
  • Material Science: The compound is used in the formulation of advanced materials, especially in coatings and polymers, where its unique properties can enhance durability and resistance to solvents.
  • Fluorinated Compounds Research: It is instrumental in the study of fluorinated compounds, which are important in various applications, including agrochemicals and specialty chemicals, due to their unique chemical properties.
  • Analytical Chemistry: This chemical is utilized in analytical techniques as a derivatizing agent, improving the detection and quantification of various analytes in complex mixtures.

Citations