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Catalog Number:
31903
CAS Number:
2244048-25-5
Fmoc-His(Trt)-Pro-OH
Purity:
≥ 94% (HPLC)
Documents
$30.00 /100MG
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Product Information

Fmoc-His(Trt)-Pro-OH is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its stability and ease of removal, making it an ideal choice for solid-phase peptide synthesis. The trityl (Trt) group provides additional protection for the histidine side chain, ensuring that the integrity of the amino acid is maintained throughout the synthesis process. Researchers and industry professionals can leverage this compound for the production of complex peptides, particularly those requiring precise control over functional groups and stereochemistry.

The unique structure of Fmoc-His(Trt)-Pro-OH allows for versatile applications in the pharmaceutical and biotechnology sectors, particularly in the development of therapeutic peptides and proteins. Its ability to facilitate the synthesis of bioactive compounds makes it invaluable in drug discovery and development. Additionally, the compound's compatibility with various coupling reagents enhances its utility in peptide libraries, enabling researchers to explore a wide range of biological activities. With its robust performance and reliability, Fmoc-His(Trt)-Pro-OH stands out as a preferred choice for professionals aiming to innovate in peptide chemistry.

CAS Number
2244048-25-5
Purity
≥ 94% (HPLC)
Molecular Formula
C45H40N4O5
Molecular Weight
716.8
MDL Number
MFCD31692261
PubChem ID
171934975
Appearance
White to off-white powder
Conditions
Store at ≤ -20 °C
General Information
CAS Number
2244048-25-5
Purity
≥ 94% (HPLC)
Molecular Formula
C45H40N4O5
Molecular Weight
716.8
MDL Number
MFCD31692261
PubChem ID
171934975
Appearance
White to off-white powder
Conditions
Store at ≤ -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-His(Trt)-Pro-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with specific sequences for various applications in biochemistry and molecular biology.
  • Drug Development: Its role in synthesizing peptide-based drugs is crucial, especially in developing therapeutics targeting specific diseases, including cancer and metabolic disorders.
  • Bioconjugation: The compound can be used to attach peptides to other molecules, such as antibodies or drug carriers, enhancing the efficacy and targeting of therapeutic agents.
  • Research in Protein Engineering: It aids in the design of modified proteins with enhanced stability or activity, which is essential for developing new biocatalysts or therapeutic proteins.
  • Diagnostics: Fmoc-His(Trt)-Pro-OH can be utilized in creating peptide-based assays or biosensors, improving the detection of biomarkers in clinical diagnostics.

Citations