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Catalog Number:
31897
CAS Number:
1433975-21-3
Fmoc-D-Aph(tBu-Cbm)-OH
Purity:
≥ 99.5% (HPLC, Chiral purity)
Synonym(s):
(2R)-3-[4-(tert-butylcarbamoylamino)phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
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$134.70 /1G
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Product Information

Fmoc-D-Aph(tBu-Cbm)-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound, recognized for its stability and ease of use, is particularly valuable in solid-phase peptide synthesis (SPPS), where it serves as a protecting group for amino acids. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) group, allows for selective deprotection under mild conditions, making it an ideal choice for researchers aiming to create complex peptide sequences with precision.

In addition to its applications in peptide synthesis, Fmoc-D-Aph(tBu-Cbm)-OH is also utilized in the development of pharmaceuticals and biologically active compounds. Its ability to enhance solubility and stability of peptides can lead to improved bioavailability and efficacy in therapeutic applications. Researchers in medicinal chemistry and biochemistry will find this compound indispensable for advancing their work in drug design and development, particularly in the synthesis of peptide-based therapeutics.

Synonyms
(2R)-3-[4-(tert-butylcarbamoylamino)phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS Number
1433975-21-3
Purity
≥ 99.5% (HPLC, Chiral purity)
Molecular Formula
C29H31N3O5
Molecular Weight
501.58
MDL Number
MFCD30475854
PubChem ID
134692611
Appearance
Yellow powder
Conditions
Store at ≤ - 18 °C
General Information
Synonyms
(2R)-3-[4-(tert-butylcarbamoylamino)phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
CAS Number
1433975-21-3
Purity
≥ 99.5% (HPLC, Chiral purity)
Molecular Formula
C29H31N3O5
Molecular Weight
501.58
MDL Number
MFCD30475854
PubChem ID
134692611
Appearance
Yellow powder
Conditions
Store at ≤ - 18 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-Aph(tBu-Cbm)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities.
  • Drug Development: Its unique properties facilitate the design and development of novel pharmaceuticals, particularly in targeting specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, helping to link biomolecules for therapeutic applications, enhancing drug delivery systems.
  • Research in Neuroscience: It plays a role in studies related to neuropeptides, contributing to the understanding of neurological functions and disorders.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of this compound, catering to specific research needs in academia and industry.

Citations