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Catalog Number:
31667
CAS Number:
220808-32-2
Fmoc-L-Tyr(3-tBu)-OH
Purity:
≥ 97.0% (HPLC)
Documents
$86.23 /25MG
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Product Information

Fmoc-L-Tyr(3-tBu)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by a tert-butyl group on the aromatic ring, enhances its stability and solubility, making it an ideal choice for researchers in organic chemistry and biochemistry.

In practical applications, Fmoc-L-Tyr(3-tBu)-OH is particularly valuable in the synthesis of bioactive peptides and pharmaceuticals, where precise control over the amino acid sequence is crucial. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups allows for the development of complex molecules with therapeutic potential. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis, leading to higher yields and purities in their final products.

CAS Number
220808-32-2
Purity
≥ 97.0% (HPLC)
Molecular Formula
C28H29NO5
Molecular Weight
459.54
MDL Number
MFCD13184920
PubChem ID
75627345
Appearance
White powder
Optical Rotation
[a]D20 = - 13 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
CAS Number
220808-32-2
Purity
≥ 97.0% (HPLC)
Molecular Formula
C28H29NO5
Molecular Weight
459.54
MDL Number
MFCD13184920
PubChem ID
75627345
Appearance
White powder
Optical Rotation
[a]D20 = - 13 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-Tyr(3-tBu)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptides for various applications.
  • Drug Development: It is used in the development of pharmaceutical compounds, especially those targeting neurological disorders, due to its ability to enhance the stability and bioavailability of peptide drugs.
  • Bioconjugation: The chemical is employed in bioconjugation processes, where it helps in attaching peptides to other biomolecules, facilitating the creation of targeted drug delivery systems.
  • Research in Cancer Therapy: Researchers utilize this compound to develop peptide-based therapeutics aimed at cancer treatment, leveraging its properties to improve efficacy and reduce side effects.
  • Protein Engineering: It plays a role in protein engineering, where it aids in modifying proteins to enhance their functionality, stability, and interaction with other molecules.

Citations