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Catalog Number:
31487
CAS Number:
246047-72-3
Grubbs Catalyst, 2nd Generation
Purity:
≥ 98% (NMR)
Synonym(s):
(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium, Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)(tricyclohexylphosphine)ruthenium(II)
Hazmat
Documents
$62.29 /100MG
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Product Information

Grubbs Catalyst, 2nd Generation, is a highly effective and versatile catalyst widely utilized in olefin metathesis reactions, making it an essential tool for chemists and researchers in organic synthesis. This catalyst is particularly valued for its ability to facilitate the formation of carbon-carbon double bonds, enabling the creation of complex molecules with high efficiency and selectivity. Its unique structure, featuring a dichlororuthenium core and tricyclohexylphosphane ligands, enhances its stability and reactivity, allowing for a broader range of substrates and reaction conditions compared to earlier generations.

This catalyst is ideal for applications in the pharmaceutical and materials science industries, where it plays a crucial role in the synthesis of fine chemicals, polymers, and advanced materials. Researchers have successfully employed Grubbs Catalyst, 2nd Generation in the development of novel drug compounds and in the production of functionalized polymers, showcasing its potential to drive innovation in synthetic methodologies. Its ease of use and effectiveness make it a preferred choice for both academic and industrial applications, providing significant advantages over similar compounds in terms of reaction rates and product yields.

Synonyms
(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium, Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)(tricyclohexylphosphine)ruthenium(II)
CAS Number
246047-72-3
Purity
≥ 98% (NMR)
Molecular Formula
C46H65Cl2N2PRu
Molecular Weight
848.97
MDL Number
MFCD03453237
PubChem ID
11147261
Melting Point
143.5-148.5 ?C
Appearance
Dark red to yellow solid
Conditions
Store at 0-8 °C
General Information
Synonyms
(1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium, Benzylidene[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(tricyclohexylphosphine)ruthenium, Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)(tricyclohexylphosphine)ruthenium(II)
CAS Number
246047-72-3
Purity
≥ 98% (NMR)
Molecular Formula
C46H65Cl2N2PRu
Molecular Weight
848.97
MDL Number
MFCD03453237
PubChem ID
11147261
Melting Point
143.5-148.5 ?C
Appearance
Dark red to yellow solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Grubbs Catalyst, 2nd Generation is widely utilized in research focused on:

  • Olefin Metathesis: This catalyst is a key player in the olefin metathesis reaction, allowing for the efficient formation of new carbon-carbon double bonds. It's particularly beneficial in the synthesis of complex organic molecules in pharmaceuticals and fine chemicals.
  • Polymer Chemistry: It plays a crucial role in the production of advanced polymers, enabling the creation of materials with tailored properties for applications in coatings, adhesives, and textiles.
  • Green Chemistry: The catalyst promotes reactions under mild conditions, reducing the need for harsh solvents and reagents, which aligns with sustainable practices in chemical manufacturing.
  • Drug Development: In medicinal chemistry, it facilitates the synthesis of intricate drug molecules, streamlining the development process and improving efficiency in pharmaceutical research.
  • Material Science: Grubbs Catalyst is used in the development of novel materials, such as self-healing polymers and advanced nanomaterials, which have applications in electronics and engineering.

Citations