Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
31031
CAS Number:
53123-88-9
Rapamycin from Streptomyces hygroscopicus
Purity:
95 - 102% (HPLC)
Synonym(s):
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
Documents
$65.40 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Rapamycin from Streptomyces hygroscopicus is a potent macrolide compound renowned for its immunosuppressive and anti-proliferative properties. This compound is widely utilized in the pharmaceutical industry, particularly in organ transplantation to prevent rejection and in oncology for its ability to inhibit tumor growth. Its mechanism of action involves the inhibition of the mTOR (mammalian target of rapamycin) pathway, making it a critical agent in research focused on cancer therapies and metabolic diseases.

In addition to its therapeutic applications, rapamycin has gained attention in the field of aging research, where it is being studied for its potential to extend lifespan and improve healthspan in various model organisms. Researchers appreciate its unique ability to modulate cellular processes, making it a valuable tool in both clinical and laboratory settings. With its diverse applications and ongoing research, rapamycin continues to hold significant promise for advancing medical science and improving patient outcomes.

Synonyms
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
CAS Number
53123-88-9
Purity
95 - 102% (HPLC)
Molecular Formula
C51H79NO13
Molecular Weight
914.17
MDL Number
MFCD00867594
PubChem ID
5040
Melting Point
183 - 185 °C
Appearance
White to off-white or yellow crystalline powder
Optical Rotation
[a]D20 = - 58.2 ° (MeOH)
Conditions
Store at - 10 °C
General Information
Synonyms
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
CAS Number
53123-88-9
Purity
95 - 102% (HPLC)
Molecular Formula
C51H79NO13
Molecular Weight
914.17
MDL Number
MFCD00867594
PubChem ID
5040
Melting Point
183 - 185 °C
Appearance
White to off-white or yellow crystalline powder
Optical Rotation
[a]D20 = - 58.2 ° (MeOH)
Conditions
Store at - 10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Rapamycin from Streptomyces hygroscopicus is widely utilized in research focused on:

  • Immunosuppression: Commonly used in organ transplantation, it helps prevent rejection by suppressing the immune response, allowing for better graft survival.
  • Cancer Treatment: Its ability to inhibit cell growth makes it valuable in oncology, particularly for certain types of tumors, providing a targeted approach to cancer therapy.
  • Cardiovascular Health: Research indicates that it may help in treating conditions like atherosclerosis by inhibiting vascular smooth muscle cell proliferation.
  • Anti-Aging Research: Studies suggest it may extend lifespan in various organisms, making it a focus in gerontology for potential applications in age-related diseases.
  • Drug Development: Used as a model compound in pharmaceutical research, it aids in the development of new drugs that target similar pathways, enhancing therapeutic options.

Citations