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Catalog Number:
30538
CAS Number:
1263047-57-9
2R,3R-(Fmoc-amino)-3-allyloxy-carbonylaminobutyric acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Abu(3R-Alloc-amino)-OH
Documents
$312.77 /100MG
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Product Information

The compound (2R,3R)-(Fmoc-amino)-3-allyloxycarbonylaminobutyric acid is a versatile building block in peptide synthesis and medicinal chemistry. Known for its protective Fmoc (9-fluorenylmethyloxycarbonyl) group, this compound facilitates the selective modification of amino acids, making it invaluable in the development of complex peptides and proteins. Its unique structure allows for the introduction of allyloxycarbonyl groups, enhancing the compound's reactivity and enabling chemists to create diverse derivatives tailored for specific applications.

This compound is particularly useful in the pharmaceutical industry, where it serves as a precursor for the synthesis of bioactive peptides, which are crucial in drug development. Researchers appreciate its ability to streamline the synthesis process, thereby improving yields and reducing the time required for peptide assembly. Additionally, its stability and compatibility with various coupling reagents make it a preferred choice for professionals looking to optimize their synthetic pathways. Overall, (2R,3R)-(Fmoc-amino)-3-allyloxycarbonylaminobutyric acid stands out for its practical applications in peptide chemistry and its potential to contribute to innovative therapeutic solutions.

Synonyms
Fmoc-D-Abu(3R-Alloc-amino)-OH
CAS Number
1263047-57-9
Purity
≥ 98% (HPLC)
Molecular Formula
C23H24N2O6
Molecular Weight
424.4
MDL Number
MFCD22989437
PubChem ID
75627324
Melting Point
165-171 ?C
Appearance
White crystallline powder
Optical Rotation
[a]D20 = +24 ± 2º (C=0.5 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Abu(3R-Alloc-amino)-OH
CAS Number
1263047-57-9
Purity
≥ 98% (HPLC)
Molecular Formula
C23H24N2O6
Molecular Weight
424.4
MDL Number
MFCD22989437
PubChem ID
75627324
Melting Point
165-171 ?C
Appearance
White crystallline powder
Optical Rotation
[a]D20 = +24 ± 2º (C=0.5 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2R,3R)-(Fmoc-amino)-3-allyloxycarbonylaminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for creating complex peptides used in pharmaceuticals.
  • Drug Development: It plays a role in the development of new drugs, particularly in designing compounds that can interact with biological targets effectively, enhancing the efficacy of therapeutic agents.
  • Bioconjugation: The chemical is used in bioconjugation processes, linking biomolecules to drugs or imaging agents, which is essential in targeted therapy and diagnostics in medicine.
  • Research in Cancer Therapy: Researchers utilize this compound to create novel drug candidates aimed at treating various cancers, benefiting from its ability to modify drug properties for improved delivery and action.
  • Material Science: It is also explored in the development of new materials, particularly in creating polymers with specific functionalities that can be used in biomedical applications.

Citations