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Catalog Number:
30535
CAS Number:
1229394-75-5
2R,3R-(Fmoc-amino)-3-azidobutyric acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-Abu(3R-N3)-OH
Antibiotic
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$93.14 /100MG
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Product Information

(2R,3R)-(Fmoc-amino)-3-azidobutyric acid is a versatile compound widely utilized in the fields of medicinal chemistry and bioconjugation. This compound features an azido group, which is highly reactive and can be employed in various click chemistry applications, facilitating the synthesis of complex molecules. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection, making it an excellent choice for peptide synthesis and modification. Researchers can leverage its unique properties to create novel therapeutics, enhance drug delivery systems, and develop biomaterials with tailored functionalities.

The compound's ability to participate in bioorthogonal reactions opens up avenues for targeted drug delivery and imaging applications, particularly in cancer research. Its stability and compatibility with various reaction conditions make it an ideal candidate for use in diverse synthetic pathways. With its significant potential in advancing research and development, (2R,3R)-(Fmoc-amino)-3-azidobutyric acid stands out as a valuable tool for professionals seeking innovative solutions in chemical synthesis and biomedical applications.

Synonyms
Fmoc-D-Abu(3R-N3)-OH
CAS Number
1229394-75-5
Purity
≥ 98% (HPLC)
Molecular Formula
C19H18N4O4
Molecular Weight
366.4
MDL Number
MFCD21363168
PubChem ID
14683492
Melting Point
147-154 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -13 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Abu(3R-N3)-OH
CAS Number
1229394-75-5
Purity
≥ 98% (HPLC)
Molecular Formula
C19H18N4O4
Molecular Weight
366.4
MDL Number
MFCD21363168
PubChem ID
14683492
Melting Point
147-154 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -13 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

(2R,3R)-(Fmoc-amino)-3-azidobutyric acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of azido groups that can facilitate further modifications.
  • Bioconjugation: Its azido group enables click chemistry applications, making it ideal for bioconjugation processes in drug development and diagnostics, enhancing the specificity and efficacy of therapeutic agents.
  • Drug Development: Researchers leverage this compound in the design of novel drug candidates, particularly in the development of targeted therapies that require precise molecular interactions.
  • Material Science: The compound can be used to create functionalized polymers and materials, which are valuable in creating smart materials with specific properties for various applications, including sensors and drug delivery systems.
  • Biological Research: It is instrumental in studying protein interactions and cellular processes, providing insights that can lead to advancements in understanding diseases and developing new treatment strategies.

Citations