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Catalog Number:
30533
CAS Number:
824955-27-3
Nα-Fmoc-S-Palmitoyl-L-cysteine
Purity:
≥ 99% (HPLC, TLC)
Synonym(s):
Fmoc-L-Cys(Palm)-OH
Documents
$72.31 /100MG
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Product Information

Na-Fmoc-S-Palmitoyl-L-cysteine is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This derivative of L-cysteine features a palmitoyl group, enhancing its hydrophobic properties, which is particularly beneficial for improving membrane permeability and stability in biological systems. Its Fmoc (9-fluorenylmethyloxycarbonyl) protective group allows for selective deprotection during synthesis, making it an essential tool for researchers in the fields of medicinal chemistry and drug development.

This compound is especially relevant in the development of peptide-based therapeutics and nanocarriers, where its unique structure facilitates the incorporation of cysteine into peptides, enabling the formation of disulfide bonds that are crucial for maintaining the structural integrity of proteins. Additionally, Na-Fmoc-S-Palmitoyl-L-cysteine can be employed in the design of lipidated peptides, which have shown promise in enhancing the bioavailability and efficacy of therapeutic agents. Its ability to improve solubility and stability in various formulations makes it a valuable asset for researchers and industry professionals alike.

Synonyms
Fmoc-L-Cys(Palm)-OH
CAS Number
824955-27-3
Purity
≥ 99% (HPLC, TLC)
Molecular Formula
C34H47NO5S
Molecular Weight
581.8
MDL Number
MFCD02094405
PubChem ID
73101113
Melting Point
90 - 92 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -47 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Cys(Palm)-OH
CAS Number
824955-27-3
Purity
≥ 99% (HPLC, TLC)
Molecular Formula
C34H47NO5S
Molecular Weight
581.8
MDL Number
MFCD02094405
PubChem ID
73101113
Melting Point
90 - 92 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -47 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-S-Palmitoyl-L-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling researchers to create complex peptide structures efficiently.
  • Drug Development: Its unique properties allow for the development of novel drug candidates, especially in the field of targeted therapies, enhancing the efficacy of pharmaceuticals.
  • Bioconjugation: The compound is used to attach biomolecules to surfaces or other molecules, facilitating the creation of bioconjugates for diagnostics and therapeutic applications.
  • Nanotechnology: In nanomedicine, it aids in the formulation of nanoparticles that can deliver drugs more effectively, improving treatment outcomes in various diseases.
  • Cosmetic Formulations: Its properties make it suitable for use in cosmetic products, providing skin benefits and enhancing product stability, appealing to the beauty industry.

Citations