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Catalog Number:
30479
CAS Number:
206183-06-4
2-(Fmoc-amino)-4-(bis-Boc-guanidino)-L-butyric acid
Purity:
≥ 99.9% (Chiral HPLC)
Synonym(s):
Fmoc-L-Agb(Boc)2-OH, (S-Na-Fmoc-,NN-bis-Boc-2-Amino-3-guanidino butanoic acid
Documents
$88.63 /100MG
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Product Information

2-(Fmoc-amino)-4-(bis-Boc-guanidino)-L-butyric acid is a versatile compound widely utilized in peptide synthesis and drug development. This compound features a unique structure that combines the protective Fmoc (9-fluorenylmethoxycarbonyl) and Boc (tert-butyloxycarbonyl) groups, making it an excellent choice for researchers focused on synthesizing complex peptides with enhanced stability and solubility. Its ability to facilitate the introduction of guanidino functionalities allows for the development of bioactive peptides, which are crucial in therapeutic applications, particularly in the fields of oncology and immunology.

The compound's specific properties, such as its high purity and stability under various conditions, make it particularly advantageous for use in solid-phase peptide synthesis (SPPS). Researchers can leverage its unique characteristics to streamline the synthesis process, reduce side reactions, and improve overall yield. Additionally, its role in the development of peptide-based drugs highlights its importance in pharmaceutical research, where it can contribute to the creation of novel therapeutics with improved efficacy and safety profiles.

Synonyms
Fmoc-L-Agb(Boc)2-OH, (S-Na-Fmoc-,NN-bis-Boc-2-Amino-3-guanidino butanoic acid
CAS Number
206183-06-4
Purity
≥ 99.9% (Chiral HPLC)
Molecular Formula
C30H38N4O8
Molecular Weight
582.6
MDL Number
MFCD01632267
PubChem ID
75627343
Melting Point
> 105 ?C (dec.)
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -9 ± 2 º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-L-Agb(Boc)2-OH, (S-Na-Fmoc-,NN-bis-Boc-2-Amino-3-guanidino butanoic acid
CAS Number
206183-06-4
Purity
≥ 99.9% (Chiral HPLC)
Molecular Formula
C30H38N4O8
Molecular Weight
582.6
MDL Number
MFCD01632267
PubChem ID
75627343
Melting Point
> 105 ?C (dec.)
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -9 ± 2 º (C=1 in DMF)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(Fmoc-amino)-4-(bis-Boc-guanidino)-L-butyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity and yield.
  • Drug Development: It plays a crucial role in the design of peptide-based therapeutics, offering potential applications in treating various diseases, including cancer and metabolic disorders, due to its ability to enhance bioactivity.
  • Bioconjugation: The compound is used in bioconjugation processes, where it facilitates the attachment of peptides to other biomolecules, improving the efficacy of drug delivery systems.
  • Research in Molecular Biology: It is employed in molecular biology studies to investigate protein interactions and functions, providing insights into cellular mechanisms and disease pathways.
  • Custom Synthesis Services: Many research laboratories utilize this compound for custom synthesis services, enabling them to create tailored compounds for specific research needs or therapeutic applications.

Citations