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Catalog Number:
30455
CAS Number:
158009-03-1
S-Trityl-L-Cysteine tert-butyl ester hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
H-L-Cys(Trt)-OtBu·HCl
Documents
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Product Information

S-Trityl-L-cystine tert-butyl ester hydrochloride is a versatile compound widely utilized in the field of organic synthesis and medicinal chemistry. This compound, recognized for its unique trityl protecting group, facilitates the selective modification of cysteine residues in peptides and proteins, making it invaluable for researchers focusing on peptide synthesis and protein engineering. Its stability under various reaction conditions allows for the development of complex molecular architectures, enhancing its appeal in drug discovery and development.

In addition to its role in peptide synthesis, S-Trityl-L-cystine tert-butyl ester hydrochloride serves as a crucial intermediate in the preparation of biologically active compounds. Its ability to protect thiol groups while maintaining reactivity in other functional groups opens avenues for the design of novel therapeutics. Researchers appreciate its ease of use and the efficiency it brings to synthetic pathways, making it a preferred choice for those aiming to streamline their workflows in both academic and industrial settings.

Synonyms
H-L-Cys(Trt)-OtBu·HCl
CAS Number
158009-03-1
Purity
≥ 99% (HPLC)
Molecular Formula
C26H30ClNO2S
Molecular Weight
456.0
MDL Number
MFCD21363202
PubChem ID
69052285
Melting Point
68-74 °C
Appearance
White powder
Optical Rotation
[a]D20 = +79 ± 2º (C=1 in 96% EtOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
H-L-Cys(Trt)-OtBu·HCl
CAS Number
158009-03-1
Purity
≥ 99% (HPLC)
Molecular Formula
C26H30ClNO2S
Molecular Weight
456.0
MDL Number
MFCD21363202
PubChem ID
69052285
Melting Point
68-74 °C
Appearance
White powder
Optical Rotation
[a]D20 = +79 ± 2º (C=1 in 96% EtOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

S-Trityl-L-cystine tert-butyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing researchers to selectively modify amino acids without affecting others, thereby enhancing the efficiency of drug development.
  • Bioconjugation: It is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems in pharmaceuticals.
  • Antioxidant Research: The compound is studied for its potential antioxidant properties, making it relevant in the development of supplements and formulations aimed at reducing oxidative stress in biological systems.
  • Protein Stabilization: In protein chemistry, it helps stabilize proteins during purification and analysis, which is essential for ensuring the integrity of therapeutic proteins in biopharmaceuticals.
  • Diagnostic Applications: Its role in developing diagnostic tools, particularly in assays that detect specific biomolecules, showcases its importance in clinical research and diagnostics.

Citations