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Catalog Number:
30325
CAS Number:
920519-33-1
Fmoc-Asn(Trt)-Ser[Psi(Me,Me)Pro]-OH
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-Asn(Trt)-Ser[Y(Me,Me)Pro]-OH, (S)-3-[Ná-(9-Fluorenylmethyloxycarbonyl)-Nâ-trityl-L-asparaginyl]-2,2-dimethyloxazolidine-4-carboxylicacid
Antibiotic
Documents
$66.80 /1G
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Product Information

Fmoc-Asn(Trt)-Ser[Psi(Me,Me)Pro]-OH is a sophisticated amino acid derivative that plays a pivotal role in peptide synthesis and drug development. This compound, characterized by its unique Fmoc (fluorenylmethyloxycarbonyl) protecting group, is particularly valuable for researchers engaged in solid-phase peptide synthesis. Its trityl (Trt) protection on the asparagine side chain enhances stability and solubility, making it an ideal choice for complex peptide sequences. The incorporation of the Psi(Me,Me)Pro structure allows for the introduction of conformational constraints, which can be crucial in the design of bioactive peptides and peptidomimetics.

This compound is widely utilized in the pharmaceutical industry for the development of therapeutic peptides, particularly in the creation of cyclic peptides that exhibit improved biological activity and stability. Its unique properties facilitate the synthesis of peptides with specific functionalities, enabling researchers to explore novel drug candidates. With its ability to streamline the synthesis process while enhancing the overall efficacy of peptide-based drugs, Fmoc-Asn(Trt)-Ser[Psi(Me,Me)Pro]-OH stands out as a valuable tool for professionals in medicinal chemistry and biochemistry.

Synonyms
Fmoc-Asn(Trt)-Ser[Y(Me,Me)Pro]-OH, (S)-3-[Ná-(9-Fluorenylmethyloxycarbonyl)-Nâ-trityl-L-asparaginyl]-2,2-dimethyloxazolidine-4-carboxylicacid
CAS Number
920519-33-1
Purity
≥ 97% (HPLC)
Molecular Formula
C44H41N3O7
Molecular Weight
723.82
MDL Number
MFCD10001368
PubChem ID
91886424
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Asn(Trt)-Ser[Y(Me,Me)Pro]-OH, (S)-3-[Ná-(9-Fluorenylmethyloxycarbonyl)-Nâ-trityl-L-asparaginyl]-2,2-dimethyloxazolidine-4-carboxylicacid
CAS Number
920519-33-1
Purity
≥ 97% (HPLC)
Molecular Formula
C44H41N3O7
Molecular Weight
723.82
MDL Number
MFCD10001368
PubChem ID
91886424
Appearance
White to off-white powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Asn(Trt)-Ser[Psi(Me,Me)Pro]-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development and molecular biology.
  • Drug Development: Its unique properties enable the design of peptide-based therapeutics, particularly in targeting specific diseases, enhancing efficacy and reducing side effects compared to traditional small molecules.
  • Bioconjugation: The compound can be used in bioconjugation techniques, facilitating the attachment of peptides to other biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Protein Engineering: It plays a significant role in protein engineering, allowing scientists to modify proteins for improved stability and functionality, which is crucial in therapeutic applications.
  • Analytical Chemistry: This compound is also valuable in analytical methods, helping researchers to study interactions between biomolecules, which can lead to breakthroughs in understanding biological processes.

Citations