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Catalog Number:
30322
CAS Number:
168216-05-5
Fmoc-Val-Thr[Psi(Me,Me)Pro]-OH
Purity:
95 - 105% (Assay by titration)
Synonym(s):
Fmoc-Val-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-valinyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
Antibiotic
Documents
$83.20 /1G
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Product Information

Fmoc-Val-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry and biochemistry due to its unique structural features, which enhance the stability and bioactivity of peptides. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection during synthesis, making it an essential tool for researchers looking to create complex peptide sequences with precision.

In practical applications, Fmoc-Val-Thr[Psi(Me,Me)Pro]-OH is utilized in the development of peptide-based therapeutics, including those targeting specific diseases such as cancer and metabolic disorders. Its ability to mimic natural amino acids while providing enhanced stability makes it a preferred choice for researchers aiming to optimize peptide properties. Additionally, this compound's unique configuration can lead to improved pharmacokinetic profiles, making it a valuable asset in drug formulation. With its significant potential in both research and therapeutic applications, Fmoc-Val-Thr[Psi(Me,Me)Pro]-OH stands out as a versatile compound for professionals in the pharmaceutical and biotechnology sectors.

Synonyms
Fmoc-Val-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-valinyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
168216-05-5
Purity
95 - 105% (Assay by titration)
Molecular Formula
C27H32N2O6
Molecular Weight
480.56
MDL Number
MFCD18427722
PubChem ID
102602281
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -24.5 ± 2.5 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Val-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-valinyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
168216-05-5
Purity
95 - 105% (Assay by titration)
Molecular Formula
C27H32N2O6
Molecular Weight
480.56
MDL Number
MFCD18427722
PubChem ID
102602281
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -24.5 ± 2.5 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Val-Thr[Psi(Me,Me)Pro]-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the pharmaceutical industry where custom peptides are developed for drug discovery and therapeutic applications.
  • Drug Development: Its unique structure allows for the creation of novel peptide-based drugs, enhancing the effectiveness of treatments for various diseases, including cancer and metabolic disorders.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking peptides to other biomolecules, which is essential in creating targeted therapies and diagnostic tools.
  • Research in Protein Engineering: It aids in the design of modified proteins with improved stability and activity, making it valuable for researchers working on enzyme engineering and synthetic biology.
  • Academic Research: This compound is frequently used in academic laboratories for studies related to peptide chemistry, providing insights into molecular interactions and biological functions.

Citations