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Catalog Number:
30319
CAS Number:
1266350-99-5
Fmoc-Ser(tBu)-Thr[Psi(Me,Me)Pro]-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-Ser(tBu)-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-O-tert-butyl-L-serinyl]-2,2,5-trimethyloxazolidine-4-carboxylic acid
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Product Information

Fmoc-Ser(tBu)-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, including the t-butyl (tBu) side chain and the Psi(Me,Me)Pro configuration, enhances stability and solubility, making it an ideal choice for researchers focusing on complex peptide sequences.

In practical applications, Fmoc-Ser(tBu)-Thr[Psi(Me,Me)Pro]-OH is particularly valuable in the development of therapeutic peptides, where precise control over amino acid sequences is crucial. Its ability to facilitate the formation of stable peptide bonds allows for the creation of more effective drug candidates. Additionally, this compound can be employed in the study of protein interactions and enzyme mechanisms, providing insights that are vital for advancing biochemistry and pharmacology. Researchers benefit from its high purity and reliability, ensuring consistent results in their experiments.

Synonyms
Fmoc-Ser(tBu)-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-O-tert-butyl-L-serinyl]-2,2,5-trimethyloxazolidine-4-carboxylic acid
CAS Number
1266350-99-5
Purity
≥ 98% (HPLC)
Molecular Formula
C29H36N2O7
Molecular Weight
524.61
MDL Number
MFCD10001374
PubChem ID
91886466
Appearance
White to beige powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Ser(tBu)-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-O-tert-butyl-L-serinyl]-2,2,5-trimethyloxazolidine-4-carboxylic acid
CAS Number
1266350-99-5
Purity
≥ 98% (HPLC)
Molecular Formula
C29H36N2O7
Molecular Weight
524.61
MDL Number
MFCD10001374
PubChem ID
91886466
Appearance
White to beige powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Ser(tBu)-Thr[Psi(Me,Me)Pro] is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex sequences with specific functionalities, which is crucial in drug development and biological research.
  • Drug Development: Its unique structure enhances the stability and solubility of peptide-based drugs, making it an essential component in pharmaceutical formulations aimed at improving therapeutic efficacy.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it facilitates the attachment of biomolecules to drugs or imaging agents, enhancing targeted delivery and reducing side effects in treatments.
  • Protein Engineering: Researchers utilize this compound in the modification of proteins, enabling the design of novel proteins with tailored properties for applications in biotechnology and medicine.
  • Research on Enzyme Inhibition: It plays a role in studies aimed at understanding enzyme mechanisms, providing insights that can lead to the development of new inhibitors for therapeutic applications.

Citations