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Catalog Number:
30311
CAS Number:
957780-52-8
Fmoc-Ile-Thr[Psi(Me,Me)Pro]-OH
Purity:
95 - 101% (Assay by titration)
Synonym(s):
Fmoc-Ile-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-isoleucinyl]-2,2,5-trimethyloxazolidine-4-carboxylic acid
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Product Information

Fmoc-Ile-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique structure that enhances its stability and bioactivity, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains, facilitating the synthesis of complex peptides with specific functionalities.

This compound is particularly beneficial in the design of peptide-based therapeutics, where precise control over amino acid sequences is essential. Researchers have utilized Fmoc-Ile-Thr[Psi(Me,Me)Pro]-OH in the development of novel peptides that exhibit improved pharmacological properties, such as enhanced receptor binding and increased resistance to enzymatic degradation. Its unique features, including the Psi(Me,Me)Pro modification, provide advantages over traditional amino acids, allowing for greater flexibility and stability in peptide structures. This compound is ideal for professionals seeking to innovate in peptide synthesis and drug formulation.

Synonyms
Fmoc-Ile-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-isoleucinyl]-2,2,5-trimethyloxazolidine-4-carboxylic acid
CAS Number
957780-52-8
Purity
95 - 101% (Assay by titration)
Molecular Formula
C28H34N2O6
Molecular Weight
494.59
MDL Number
MFCD18427359
PubChem ID
129011250
Appearance
White to off-white powder
Optical Rotation
[a]25D = -24.5 ± 2.5 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Ile-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-isoleucinyl]-2,2,5-trimethyloxazolidine-4-carboxylic acid
CAS Number
957780-52-8
Purity
95 - 101% (Assay by titration)
Molecular Formula
C28H34N2O6
Molecular Weight
494.59
MDL Number
MFCD18427359
PubChem ID
129011250
Appearance
White to off-white powder
Optical Rotation
[a]25D = -24.5 ± 2.5 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Ile-Thr[Psi(Me,Me)Pro]-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, enabling researchers to create complex sequences for various biological studies.
  • Drug Development: It plays a crucial role in the design of peptide-based drugs, particularly in targeting specific receptors, which can lead to more effective therapies with fewer side effects.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing for the attachment of peptides to other molecules, enhancing the delivery and efficacy of therapeutic agents.
  • Protein Engineering: Researchers utilize it to modify proteins, improving their stability and functionality, which is essential in developing new biotechnological applications.
  • Research in Neuroscience: Its unique structure makes it valuable in studies related to neuropeptides, helping scientists understand brain functions and develop treatments for neurological disorders.

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Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Product Specification (PS)

The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

*Catalog Number
The Catalog Number is a five-digit number located on the product label near the product name, and also in your order confirmation email. Exclude any hyphens or size information. Ex. 01578
*Lot Number
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Certificates Of Origin (COO)

This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.

*Catalog Number
The Catalog Number is a five-digit number located on the product label near the product name, and also in your order confirmation email. Exclude any hyphens or size information. Ex. 01578
*Lot Number
The Lot Number is a multi-digit number that can be found on the product label or invoice. Ex. 12345-12345
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