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Catalog Number:
30309
CAS Number:
1262308-49-5
Fmoc-Gly-Thr[Psi(Me,Me)Pro]-OH
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-Gly-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R-3-[N-(9-Fluorenylmethyloxycarbonyl)-glycinyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
Antibiotic
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$70.00 /1G
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Product Information

Fmoc-Gly-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, incorporating a Psi(Me,Me)Pro residue, enhances the stability and bioactivity of peptides, making it an invaluable tool for researchers in medicinal chemistry and biochemistry.

The compound's ability to facilitate the synthesis of complex peptides allows for the exploration of novel therapeutic agents, particularly in the fields of oncology and neurobiology. Its application in the development of peptide-based drugs can lead to improved efficacy and reduced side effects compared to traditional small-molecule drugs. Additionally, Fmoc-Gly-Thr[Psi(Me,Me)Pro]-OH is recognized for its compatibility with various coupling reagents, streamlining the peptide synthesis process and enhancing overall yield. This makes it an essential component for researchers aiming to innovate in peptide therapeutics.

Synonyms
Fmoc-Gly-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R-3-[N-(9-Fluorenylmethyloxycarbonyl)-glycinyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
1262308-49-5
Purity
≥ 99% (HPLC)
Molecular Formula
C24H26N2O6
Molecular Weight
438.48
MDL Number
MFCD18427358
PubChem ID
91976837
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -31 ± 2 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Gly-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R-3-[N-(9-Fluorenylmethyloxycarbonyl)-glycinyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
1262308-49-5
Purity
≥ 99% (HPLC)
Molecular Formula
C24H26N2O6
Molecular Weight
438.48
MDL Number
MFCD18427358
PubChem ID
91976837
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -31 ± 2 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Gly-Thr[Psi(Me,Me)Pro]-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: It plays a significant role in the development of peptide-based therapeutics, offering potential treatments for various diseases by enhancing the stability and bioactivity of drug candidates.
  • Bioconjugation: The compound is used in bioconjugation techniques, facilitating the attachment of peptides to other biomolecules, which is essential for creating targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the modification of proteins, allowing scientists to study protein interactions and functions, which is vital for understanding biological processes.
  • Analytical Chemistry: This chemical is utilized in analytical methods to characterize peptides and proteins, providing insights into their structure and function, which is important for quality control in pharmaceutical manufacturing.

Citations