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Catalog Number:
30307
CAS Number:
957780-56-2
Fmoc-Glu(OtBu)-Thr[Psi(Me,Me)Pro]-OH
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-Glu(OtBu)-Thr[Ψ(Me,Me)Pro]-OH
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Product Information

Fmoc-Glu(OtBu)-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its effectiveness in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptides. The presence of the tert-butyl (OtBu) group enhances its stability and solubility, making it an ideal choice for researchers focused on synthesizing modified peptides with improved pharmacological properties.

This compound is particularly valuable in the development of peptide-based therapeutics, where precise modifications can lead to enhanced bioactivity and selectivity. Its unique structure allows for the incorporation of specific functionalities that can be tailored for various applications, including drug delivery systems and targeted therapies. Researchers in medicinal chemistry and biochemistry will find Fmoc-Glu(OtBu)-Thr[Psi(Me,Me)Pro]-OH to be an essential tool in their quest to design and synthesize innovative peptide constructs.

Synonyms
Fmoc-Glu(OtBu)-Thr[Ψ(Me,Me)Pro]-OH
CAS Number
957780-56-2
Purity
≥ 97% (HPLC)
Molecular Formula
C31H38N2O8
Molecular Weight
566.65
MDL Number
MFCD18427360
PubChem ID
129011248
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -25 ± 2.5 º (Lit.)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Glu(OtBu)-Thr[Ψ(Me,Me)Pro]-OH
CAS Number
957780-56-2
Purity
≥ 97% (HPLC)
Molecular Formula
C31H38N2O8
Molecular Weight
566.65
MDL Number
MFCD18427360
PubChem ID
129011248
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -25 ± 2.5 º (Lit.)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Glu(OtBu)-Thr[Psi(Me,Me)Pro] is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex and diverse peptide sequences.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, enhancing the stability and bioavailability of therapeutic peptides.
  • Bioconjugation: Researchers use this chemical for bioconjugation applications, enabling the attachment of peptides to various biomolecules, which is essential for creating targeted drug delivery systems.
  • Protein Engineering: In the field of protein engineering, it aids in the modification of proteins to improve their functionality, stability, and interaction with other biological molecules.
  • Research in Neuroscience: The compound is utilized in neuroscience research to study peptide interactions in the brain, contributing to the understanding of neuropeptides and their roles in signaling pathways.

Citations