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Catalog Number:
29780
CAS Number:
132622-68-5
2S,4R)-Boc-4-azido-pyrrolidine-2-carboxylic acid·DCHA
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-trans-Pro(4-azido)-OH·DCHA
Antibiotic
Documents
$120.88 /250MG
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Product Information

The compound (2S,4R)-Boc-4-azido-pyrrolidine-2-carboxylic acid·DCHA is a versatile building block in organic synthesis, particularly valued for its azido group, which facilitates further functionalization in medicinal chemistry and materials science. This compound is often utilized in the development of novel pharmaceuticals, where its unique structural features allow for the introduction of diverse functional groups through click chemistry. Its Boc (tert-butyloxycarbonyl) protecting group enhances stability during synthesis, making it an ideal candidate for multi-step reactions. Researchers appreciate its application in the synthesis of peptide mimetics and other biologically active compounds, where the azido group can be converted into amines or other functionalities, expanding the scope of potential therapeutic agents.

In addition to its pharmaceutical applications, (2S,4R)-Boc-4-azido-pyrrolidine-2-carboxylic acid·DCHA is also relevant in polymer chemistry, where it can be incorporated into polymer backbones to impart unique properties. Its ability to undergo further transformations makes it a valuable tool for chemists looking to innovate in drug design and materials development. The compound's stability and reactivity profile position it as a preferred choice for researchers aiming to explore new chemical spaces.

Synonyms
Boc-trans-Pro(4-azido)-OH·DCHA
CAS Number
132622-68-5
Purity
≥ 98% (HPLC)
Molecular Formula
C10H16N4O4·C12H23N
Molecular Weight
437.58
MDL Number
MFCD12923197
PubChem ID
14842620
Appearance
White powder
Optical Rotation
[a]20D = -30 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-trans-Pro(4-azido)-OH·DCHA
CAS Number
132622-68-5
Purity
≥ 98% (HPLC)
Molecular Formula
C10H16N4O4·C12H23N
Molecular Weight
437.58
MDL Number
MFCD12923197
PubChem ID
14842620
Appearance
White powder
Optical Rotation
[a]20D = -30 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

(2S,4R)-Boc-4-azido-pyrrolidine-2-carboxylic acid·DCHA is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of novel therapeutics. Its azido group allows for click chemistry, facilitating the creation of complex peptide structures.
  • Drug Development: The unique properties of this compound make it valuable in drug discovery. Researchers can modify its structure to enhance bioactivity and selectivity, which is crucial in designing effective pharmaceuticals.
  • Bioconjugation: Its azido functionality is ideal for bioconjugation applications, allowing for the attachment of drugs or imaging agents to biomolecules. This is particularly useful in targeted drug delivery systems.
  • Material Science: The compound can be used in the development of functional materials, such as hydrogels or coatings, that require specific chemical properties. Its versatility allows for customization in various applications.
  • Research in Chemical Biology: It is employed in chemical biology studies to explore protein interactions and cellular processes. The ability to introduce azide groups into biomolecules aids in understanding biological mechanisms.

Citations