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Catalog Number:
29777
CAS Number:
1417789-17-3
(S)-Fmoc-2-amino-5-(tritylthio)-pentanoic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
(S)-Fmoc-2-amino-5-tritylsulfanyl-pentanoic acid
Documents
$200.00 /100MG
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Product Information

(S)-Fmoc-2-amino-5-(tritylthio)-pentanoic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during peptide chain assembly. Its unique tritylthio moiety enhances stability and solubility, making it an ideal choice for researchers focusing on complex peptide structures.

In practical applications, (S)-Fmoc-2-amino-5-(tritylthio)-pentanoic acid is particularly valuable in the development of peptide-based therapeutics and in the synthesis of bioactive compounds. Its ability to facilitate the formation of disulfide bonds and its compatibility with various coupling reagents make it a preferred choice for chemists aiming to create high-purity peptides. This compound not only streamlines the synthesis process but also improves yields, making it a reliable option for both academic research and industrial applications.

Synonyms
(S)-Fmoc-2-amino-5-tritylsulfanyl-pentanoic acid
CAS Number
1417789-17-3
Purity
≥ 98% (HPLC)
Molecular Formula
C39H35NO4S
Molecular Weight
613.77
MDL Number
MFCD21364742
PubChem ID
138108386
Appearance
White to off-white solid
Optical Rotation
[a]D20 = 8.5 ± 2 º (C=1 in Ethyl Acetate)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(S)-Fmoc-2-amino-5-tritylsulfanyl-pentanoic acid
CAS Number
1417789-17-3
Purity
≥ 98% (HPLC)
Molecular Formula
C39H35NO4S
Molecular Weight
613.77
MDL Number
MFCD21364742
PubChem ID
138108386
Appearance
White to off-white solid
Optical Rotation
[a]D20 = 8.5 ± 2 º (C=1 in Ethyl Acetate)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-5-(tritylthio)-pentanoic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS). Its protective Fmoc group allows for selective deprotection, making it easier to assemble complex peptide chains.
  • Drug Development: The compound is valuable in pharmaceutical research for developing new drugs, especially those targeting specific biological pathways. Its unique structure can enhance the bioavailability and effectiveness of therapeutic agents.
  • Bioconjugation: In biochemistry, it is used for attaching peptides to various biomolecules, facilitating the design of targeted drug delivery systems. This application is particularly beneficial in cancer therapy, where precision is crucial.
  • Research in Neuroscience: The compound's properties make it suitable for creating peptide-based probes that can interact with specific receptors in the nervous system, aiding in the study of neuropharmacology.
  • Protein Engineering: It is employed in the modification of proteins to enhance their stability and functionality. This application is significant in biotechnology, where engineered proteins can be used in diagnostics or therapeutics.

Citations