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Catalog Number:
29756
CAS Number:
159610-89-6
Na-Fmoc-Ne-azide-L-Lysine
Purity:
≥ 99.7% (Chiral HPLC)
Synonym(s):
Fmoc-Lys(N3)-OH, Fmoc-e-azido-Nle-OH
Documents
$55.00 /100MG
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Product Information

Fmoc-Lys(N3)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protective group, which is essential for the selective protection of amine functionalities during the synthesis of peptides. The azido group (N3) enhances its reactivity, making it an excellent candidate for click chemistry applications, particularly in the development of bioconjugates and targeted therapeutics. Researchers appreciate its stability under various conditions, allowing for streamlined synthesis processes in both academic and industrial settings.

In addition to its role in peptide synthesis, Fmoc-Lys(N3)-OH is also employed in the creation of novel biomaterials and drug delivery systems. Its unique properties facilitate the incorporation of bioactive molecules, enabling the design of targeted therapies with improved efficacy. The compound's ability to undergo selective reactions further expands its utility in medicinal chemistry, making it a valuable tool for researchers aiming to innovate in drug design and development.

Synonyms
Fmoc-Lys(N3)-OH, Fmoc-e-azido-Nle-OH
CAS Number
159610-89-6
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C21H22N4O4
Molecular Weight
394.43
MDL Number
MFCD13182319
PubChem ID
19048662
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -12.0 to -14.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-Lys(N3)-OH, Fmoc-e-azido-Nle-OH
CAS Number
159610-89-6
Purity
≥ 99.7% (Chiral HPLC)
Molecular Formula
C21H22N4O4
Molecular Weight
394.43
MDL Number
MFCD13182319
PubChem ID
19048662
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -12.0 to -14.5 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Lys(N3)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of azide groups for further modifications.
  • Bioconjugation: Its azide functionality enables efficient bioconjugation reactions, such as click chemistry, facilitating the attachment of various biomolecules for drug development and diagnostic applications.
  • Drug Delivery Systems: Researchers leverage this compound in the design of advanced drug delivery systems, where its properties can enhance the stability and targeting of therapeutic agents.
  • Protein Engineering: Fmoc-Lys(N3)-OH is used in the modification of proteins, allowing scientists to introduce specific functionalities that can alter protein behavior for research and therapeutic purposes.
  • Fluorescent Labeling: The compound can be utilized in the development of fluorescently labeled peptides, which are essential for tracking and imaging in biological studies.

Citations