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Catalog Number:
29704
CAS Number:
376592-37-9
Fmoc-L-2,5,7-tri-tert-butyl-tryptophan
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Tbt-OH
Documents
$127.79 /25MG
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Product Information

Fmoc-L-2,5,7-tri-tert-butyl-tryptophan is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry due to its unique structure, which enhances the stability and solubility of peptides. Its tert-butyl groups provide significant steric hindrance, making it an excellent choice for researchers looking to create more robust and stable peptide chains. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy deprotection during synthesis, facilitating the production of complex peptides with high purity and yield.

In practical applications, Fmoc-L-2,5,7-tri-tert-butyl-tryptophan is widely utilized in the synthesis of bioactive peptides, which can be essential in drug discovery and development. Its ability to improve the pharmacokinetic properties of peptides makes it a preferred choice among researchers in pharmaceutical and biotechnological industries. Additionally, this compound can be employed in the development of peptide-based therapeutics, including those targeting cancer and other diseases, showcasing its potential in advancing medical research and treatment options.

Synonyms
Fmoc-L-Tbt-OH
CAS Number
376592-37-9
Purity
≥ 98% (HPLC)
Molecular Formula
C38H46N2O4
Molecular Weight
594.79
MDL Number
MFCD18782843
PubChem ID
22483950
Appearance
White solid
Optical Rotation
[a]D20 = 4.4 ± 1.8 º (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Tbt-OH
CAS Number
376592-37-9
Purity
≥ 98% (HPLC)
Molecular Formula
C38H46N2O4
Molecular Weight
594.79
MDL Number
MFCD18782843
PubChem ID
22483950
Appearance
White solid
Optical Rotation
[a]D20 = 4.4 ± 1.8 º (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-2,5,7-tri-tert-butyl-tryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly for creating complex structures in pharmaceutical research.
  • Drug Development: Its unique properties enhance the stability and bioavailability of drug candidates, making it valuable in the development of new therapeutics.
  • Bioconjugation: The chemical is used in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in diagnostics and targeted drug delivery.
  • Material Science: It finds applications in the development of advanced materials, such as polymers and nanomaterials, due to its ability to modify surface properties.
  • Research in Neuroscience: The compound is also explored in neuroscience for its potential role in studying neurotransmitter pathways and developing neuroprotective agents.

Citations