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Catalog Number:
29702
CAS Number:
1310680-31-9
S-Fmoc-3-amino-4,4,4-trifluoro-butyric acid
Purity:
≥ 99.5% (Chiral HPLC)
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$168.35 /25MG
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Product Information

(S)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid is a valuable compound widely utilized in peptide synthesis and medicinal chemistry. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its trifluoromethyl group enhances the compound's lipophilicity, making it particularly useful in drug design and development, where increased membrane permeability is often desired. Researchers appreciate its role in the production of fluorinated peptides, which can exhibit unique biological activities and improved pharmacokinetic properties.

This compound is especially relevant in the pharmaceutical industry, where it serves as a building block for the synthesis of complex peptide-based therapeutics. Its unique properties allow for the creation of peptides with enhanced stability and efficacy, making it a preferred choice for researchers focused on developing innovative drug candidates. Additionally, (S)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid stands out for its compatibility with various coupling reagents and methodologies, streamlining the peptide synthesis process and improving overall yield.

CAS Number
1310680-31-9
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C19H16F3NO4
Molecular Weight
379.34
MDL Number
MFCD18782842
PubChem ID
22661402
Appearance
White solid
Optical Rotation
[a]20D = -12 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
CAS Number
1310680-31-9
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C19H16F3NO4
Molecular Weight
379.34
MDL Number
MFCD18782842
PubChem ID
22661402
Appearance
White solid
Optical Rotation
[a]20D = -12 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, due to its protective Fmoc group that allows for selective deprotection.
  • Drug Development: Its unique trifluoromethyl group enhances the biological activity of peptides, making it valuable in the pharmaceutical industry for developing more potent and selective drugs.
  • Bioconjugation: The compound can be used to modify biomolecules, facilitating the attachment of drugs to antibodies or other proteins, which is crucial in targeted therapy applications.
  • Research in Fluorinated Compounds: As a fluorinated amino acid, it is essential in studies exploring the effects of fluorine on the stability and activity of peptides, providing insights into new therapeutic strategies.
  • Analytical Chemistry: This chemical is used in the development of analytical methods for detecting and quantifying peptides, aiding researchers in characterizing complex mixtures in various biological samples.

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Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Product Specification (PS)

The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.

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Certificates of Analysis (COA)

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Certificates Of Origin (COO)

This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.

*Catalog Number
The Catalog Number is a five-digit number located on the product label near the product name, and also in your order confirmation email. Exclude any hyphens or size information. Ex. 01578
*Lot Number
The Lot Number is a multi-digit number that can be found on the product label or invoice. Ex. 12345-12345
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Not finding what you are looking for?
Request COO
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