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Catalog Number:
29666
CAS Number:
887129-04-6
Fmoc-4-(4-chlorophenyl)-piperidine-4-carboxylic acid
Purity:
≥ 99% (HPLC)
Documents
$86.23 /100MG
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Product Information

Fmoc-4-(4-chlorophenyl)-piperidine-4-carboxylic acid is a versatile compound widely utilized in the field of peptide synthesis and drug development. This compound, known for its protective Fmoc (9-fluorenylmethoxycarbonyl) group, plays a crucial role in the solid-phase peptide synthesis process, allowing for the selective protection of amine groups during the assembly of peptide chains. Its unique structure, featuring a 4-chlorophenyl moiety, enhances its reactivity and compatibility with various coupling reagents, making it an ideal choice for researchers focusing on the synthesis of complex peptides and pharmaceutical intermediates.

In addition to its applications in peptide synthesis, Fmoc-4-(4-chlorophenyl)-piperidine-4-carboxylic acid is also valuable in medicinal chemistry, where it serves as a building block for the development of novel therapeutic agents. Its ability to facilitate the introduction of specific functional groups allows for the fine-tuning of biological activity in drug candidates. Researchers and industry professionals can leverage this compound to streamline their synthesis processes and enhance the efficacy of their products, making it a vital addition to any chemical toolkit.

CAS Number
887129-04-6
Purity
≥ 99% (HPLC)
Molecular Formula
C27H24ClNO4
Molecular Weight
461.94
MDL Number
MFCD11226816
PubChem ID
45356723
Melting Point
170-182 ºC
Appearance
White Powder
Conditions
Store at 0-8°C
General Information
CAS Number
887129-04-6
Purity
≥ 99% (HPLC)
Molecular Formula
C27H24ClNO4
Molecular Weight
461.94
MDL Number
MFCD11226816
PubChem ID
45356723
Melting Point
170-182 ºC
Appearance
White Powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-(4-chlorophenyl)-piperidine-4-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), where its protective Fmoc group allows for selective deprotection and coupling.
  • Drug Development: Its structure is beneficial in medicinal chemistry for designing novel pharmaceutical compounds, especially in targeting specific receptors due to its piperidine moiety.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules like proteins or antibodies to therapeutic agents, enhancing drug delivery systems.
  • Research in Neuroscience: Due to its structural similarity to neurotransmitters, it is explored in studies related to neuropharmacology, potentially aiding in the development of treatments for neurological disorders.
  • Material Science: The compound can be incorporated into polymer matrices, improving the mechanical properties and thermal stability of materials used in various applications.

Citations