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Catalog Number:
29649
CAS Number:
914399-98-7
(S)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-α-Me-L-Ser(tBu)-OH
Documents
$141.41 /25MG
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Product Information

(S)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique tert-butoxy group enhances solubility and stability, making it an excellent choice for researchers focused on complex peptide structures.

In the pharmaceutical industry, (S)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid is particularly valuable for the synthesis of bioactive peptides and therapeutic agents. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups allows for the efficient development of novel compounds. Additionally, this compound's favorable properties make it an ideal candidate for applications in medicinal chemistry and biochemistry, where precision and reliability are paramount.

Synonyms
Fmoc-α-Me-L-Ser(tBu)-OH
CAS Number
914399-98-7
Purity
≥ 98% (HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD26793609
PubChem ID
146025879
Appearance
White powder
Optical Rotation
[a]D20 = +9 ± 2 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-α-Me-L-Ser(tBu)-OH
CAS Number
914399-98-7
Purity
≥ 98% (HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD26793609
PubChem ID
146025879
Appearance
White powder
Optical Rotation
[a]D20 = +9 ± 2 º (C=1 in CHCl3)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: Its unique structure aids in the design of peptide-based drugs, enhancing bioavailability and stability, which is crucial in pharmaceutical formulations.
  • Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of peptides to various biomolecules, which is essential in developing targeted therapies and diagnostics.
  • Research in Neuroscience: It is applied in the synthesis of neuropeptides, contributing to studies on neurological functions and potential treatments for neurodegenerative diseases.
  • Custom Synthesis Services: Many research labs utilize this compound for custom synthesis projects, providing tailored solutions for specific research needs in academia and industry.

Citations