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Catalog Number:
29647
CAS Number:
1354752-75-2
(S)-Fmoc-2-amino-3-propargyloxy-propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Ser(propargyl)-OH
Documents
$89.83 /250MG
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Product Information

(S)-Fmoc-2-amino-3-propargyloxy-propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its propargyloxy moiety enhances the compound's reactivity, making it an excellent candidate for applications in click chemistry and other coupling reactions. Researchers appreciate its stability and ease of handling, which facilitate the synthesis of complex peptides and bioactive molecules.

In addition to its role in peptide synthesis, (S)-Fmoc-2-amino-3-propargyloxy-propionic acid has potential applications in the development of novel therapeutics, particularly in the fields of oncology and neurology. Its unique structure allows for the incorporation of diverse functionalities, enabling the design of compounds with improved efficacy and selectivity. This compound stands out for its ability to streamline the synthesis process while providing researchers with the flexibility needed to explore new chemical entities.

Synonyms
Fmoc-L-Ser(propargyl)-OH
CAS Number
1354752-75-2
Purity
≥ 98% (HPLC)
Molecular Formula
C21H19NO5
Molecular Weight
365.39
MDL Number
MFCD26793607
PubChem ID
137795335
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -5.5 ± 0.5º (C=1 in DMF) orD20 = -13 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Ser(propargyl)-OH
CAS Number
1354752-75-2
Purity
≥ 98% (HPLC)
Molecular Formula
C21H19NO5
Molecular Weight
365.39
MDL Number
MFCD26793607
PubChem ID
137795335
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -5.5 ± 0.5º (C=1 in DMF) orD20 = -13 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-3-propargyloxy-propionic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound is a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure makes it useful in the design of novel pharmaceuticals, particularly in targeting specific biological pathways, enhancing drug efficacy and selectivity.
  • Bioconjugation: The propargyloxy group enables click chemistry applications, facilitating the attachment of biomolecules to surfaces or other compounds, which is crucial in developing biosensors and targeted drug delivery systems.
  • Research in Neuroscience: This compound can be employed in studies related to neurotransmitter function and receptor interactions, providing insights into neurological disorders and potential therapeutic approaches.
  • Material Science: Its properties allow for the modification of polymeric materials, enhancing their functionality for applications in coatings, adhesives, and drug delivery systems.

Citations