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Catalog Number:
29638
CAS Number:
1354752-76-3
(R)-Fmoc-2-amino-3-propargylsulfanyl-propionic acid
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Cys(propargyl)-OH
Documents
$106.96 /100MG
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Product Information

(R)-Fmoc-2-amino-3-propargylsulfanyl-propionic acid is a versatile building block in peptide synthesis and medicinal chemistry. This compound features a unique propargylsulfanyl group, which enhances its reactivity and allows for the formation of diverse peptide structures. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group is widely recognized for its stability during synthesis, making it an ideal choice for researchers focused on developing complex peptides and biologically active compounds.

In addition to its application in peptide synthesis, (R)-Fmoc-2-amino-3-propargylsulfanyl-propionic acid is valuable in the development of novel therapeutics, particularly in the fields of cancer research and drug discovery. The compound's unique properties facilitate the introduction of sulfur-containing functionalities, which can improve the pharmacological profiles of peptide-based drugs. Researchers can leverage this compound to explore new avenues in drug design, ultimately contributing to advancements in targeted therapies.

Synonyms
Fmoc-L-Cys(propargyl)-OH
CAS Number
1354752-76-3
Purity
≥ 97% (HPLC)
Molecular Formula
C21H19NO4S
Molecular Weight
381.45
MDL Number
MFCD26793605
PubChem ID
103666929
Appearance
Off-white powder
Optical Rotation
[a]20D = -61 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Cys(propargyl)-OH
CAS Number
1354752-76-3
Purity
≥ 97% (HPLC)
Molecular Formula
C21H19NO4S
Molecular Weight
381.45
MDL Number
MFCD26793605
PubChem ID
103666929
Appearance
Off-white powder
Optical Rotation
[a]20D = -61 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-Fmoc-2-amino-3-propargylsulfanyl-propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with enhanced stability.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific biological pathways, due to its ability to modify peptide sequences effectively.
  • Bioconjugation: The compound can be used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted therapies and diagnostics.
  • Research in Neuroscience: It plays a role in studying neuropeptides and their functions, providing insights into neurological disorders and potential therapeutic approaches.
  • Material Science: The compound can be incorporated into polymer matrices, enhancing the properties of materials used in drug delivery systems, thereby improving the efficacy and control of drug release.

Citations