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Catalog Number:
29467
CAS Number:
1060769-55-2
S-Fmoc-2-amino-5-[(N'-Pbf-N''-tert-butoxy)-guanidino]-pentanoic acid
Purity:
≥ 98% (HPLC)
Documents
$260.69 /25MG
Pack Size Availability Price
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Product Information

(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-tert-butoxy)-guanidino]-pentanoic acid is a specialized amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, including the tert-butoxy and Pbf (2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl) groups, enhances its stability and reactivity, making it an excellent choice for researchers focused on developing complex peptides and biologically active compounds.

In the pharmaceutical industry, (S)-Fmoc-2-amino-5-[(N'-Pbf-N''-tert-butoxy)-guanidino]-pentanoic acid is particularly valuable for synthesizing peptide-based therapeutics, where precision and efficiency are paramount. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups allows for the creation of high-purity peptides, essential for drug efficacy and safety. This compound not only streamlines the synthesis process but also opens avenues for innovative research in medicinal chemistry and biochemistry.

CAS Number
1060769-55-2
Purity
≥ 98% (HPLC)
Molecular Formula
C38H48N4O8S
Molecular Weight
720.88
MDL Number
MFCD18782824
PubChem ID
137705345
Appearance
Off-white powder
Optical Rotation
[a]D20 = -4 ± 1º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
CAS Number
1060769-55-2
Purity
≥ 98% (HPLC)
Molecular Formula
C38H48N4O8S
Molecular Weight
720.88
MDL Number
MFCD18782824
PubChem ID
137705345
Appearance
Off-white powder
Optical Rotation
[a]D20 = -4 ± 1º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-tert-butoxy)-guanidino]-pentanoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex and functional peptide sequences.
  • Drug Development: Its unique structure makes it valuable in medicinal chemistry, where it can be used to develop new pharmaceuticals that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound can be employed in bioconjugation techniques, facilitating the attachment of biomolecules to drugs or diagnostic agents, which is crucial in targeted therapy and imaging applications.
  • Research in Protein Engineering: It plays a significant role in protein engineering, helping researchers modify proteins to improve their stability, activity, or specificity, which is essential in various biotechnological applications.
  • Academic Research: Often used in academic laboratories, it supports a wide range of studies in biochemistry and molecular biology, aiding in the exploration of new biochemical pathways and mechanisms.

Citations