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Catalog Number:
29466
CAS Number:
1060769-54-1
S-Fmoc-2-amino-5-[(N'-Pbf-N''-Boc-amino)-guanidino]-pentanoic acid
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-L-Arg(Boc-NH)(Pbf)-OH
Documents
$221.63 /25MG
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Product Information

(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-Boc-amino)-guanidino]-pentanoic acid is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a protective Fmoc group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its unique structure, incorporating both Pbf and Boc protecting groups, enhances stability and reactivity, making it an ideal choice for researchers focused on complex peptide sequences.

In pharmaceutical research, this compound plays a crucial role in the design of peptide-based therapeutics, particularly in the development of inhibitors and biologically active peptides. Its ability to provide multiple functional groups allows for the introduction of various modifications, thereby expanding the potential applications in medicinal chemistry. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in yielding high-purity peptides, which are essential for biological assays and drug formulation.

Synonyms
Fmoc-L-Arg(Boc-NH)(Pbf)-OH
CAS Number
1060769-54-1
Purity
≥ 95% (HPLC)
Molecular Formula
C39H49N5O9S
Molecular Weight
763.91
MDL Number
MFCD18782823
PubChem ID
138114152
Appearance
White powder
Optical Rotation
[α]D20 = -5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Arg(Boc-NH)(Pbf)-OH
CAS Number
1060769-54-1
Purity
≥ 95% (HPLC)
Molecular Formula
C39H49N5O9S
Molecular Weight
763.91
MDL Number
MFCD18782823
PubChem ID
138114152
Appearance
White powder
Optical Rotation
[α]D20 = -5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-5-[(N'-Pbf-N''-Boc-amino)-guanidino]-pentanoic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex structures efficiently.
  • Drug Development: It plays a significant role in the development of peptide-based therapeutics, offering potential treatments for various diseases, including cancer and metabolic disorders.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, enhancing their efficacy and targeting capabilities.
  • Research in Molecular Biology: It aids in the study of protein interactions and functions, providing insights into cellular mechanisms and disease pathways, which is crucial for advancing biomedical research.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis of this compound, catering to specific research needs, thus facilitating tailored solutions for scientists and researchers.

Citations